Votre recherche pour: 4-Methoxy-2,3,5-trifluorobenzoic+acid

Numéro de catalogue: (APOSOR471368-1G)

Fournisseur: Apollo Scientific

Description: 2-(Chloromethyl)-6-methoxyquinazoline

UOM: 1 * 1 g

Promotion

Fournisseur: Thermo Fisher Scientific

Description: 4-(Chloromethyl)benzonitrile 98%

MSMD

Fournisseur: Apollo Scientific

Description: 3-(Chloromethyl)phenol 95%

Numéro de catalogue: (APOSOR103008-5G)

Fournisseur: Apollo Scientific

Description: 2-(Chloromethyl)benzothiazole

UOM: 1 * 5 g

Promotion

Fournisseur: Apollo Scientific

Description: 3-(Chloromethyl)-N,N-dimethylbenzamide 98%

Numéro de catalogue: (BOSSBS-7571R-A350)

Fournisseur: Bioss

Description: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).

UOM: 1 * 100 µl

Promotion

Fournisseur: Thermo Fisher Scientific

Description: 9-(Chlorométhyl)anthracene 98+%

MSMD

Fournisseur: Apollo Scientific

Description: 4-(Chloromethyl)-2-isopropylthiazole, grade technique

Fournisseur: Apollo Scientific

Description: 4-(Chloromethyl)benzaldehyde

Fournisseur: Apollo Scientific

Description: 4-Chlorométhyl-o-xylène 70%

Numéro de catalogue: (BOSSBS-7571R-A750)

Fournisseur: Bioss

Description: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerisation (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).

UOM: 1 * 100 µl

Promotion

Fournisseur: Thermo Fisher Scientific

Description: 2-(Chloromethyl)benzoxazole 97%

MSMD

Fournisseur: Thermo Fisher Scientific

Description: (Chlorométhyl)triméthylsilane 98+%

MSMD

Numéro de catalogue: (APOSOR950620-1G)

Fournisseur: Apollo Scientific

Description: 2-(Chloromethyl)-5-methoxypyridine 95%

UOM: 1 * 1 g

Promotion

Numéro de catalogue: (PRSI25-927)

Fournisseur: ProSci Inc.

Description: SLC23A3 is a multi-pass membrane protein. It belongs to the xanthine/uracil permease family, SLC23A subfamily. The exact function of SLC23A3 remains unknown.

UOM: 1 * 50 µG

Promotion

Fournisseur: Apollo Scientific

Description: Chloromethyl benzoate 98%