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Image non disponible-MOLEM20959741

Uridine

Numéro de catalogue: (MOLEM20959741)
Fournisseur: Molekula
Description: Uridine
UOM: 1 * 25 g

Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.

Image non disponible-ROTH0714.3

Uridine

Fournisseur: Roth Carl
Description: Uridine

Image non disponible-APOSOR103007-1G

2-(Chloromethyl)benzoxazole

Fournisseur: Apollo Scientific
Description: 2-(Chloromethyl)benzoxazole

Image non disponible-SERA37850.03

Uridine

Numéro de catalogue: (SERA37850.03)
Fournisseur: Serva
Description: Uridine
UOM: 1 * 100 g

Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.

Image non disponible-APOSOR4920-1G

2-(Chloromethyl)-4-hydroxyquinazoline

Numéro de catalogue: (APOSOR4920-1G)
Fournisseur: Apollo Scientific
Description: 2-(Chloromethyl)-4-hydroxyquinazoline
UOM: 1 * 1 g
Image non disponible-APOSOR301217-250MG

2-(Chloromethyl)oxazole

Fournisseur: Apollo Scientific
Description: 2-(Chloromethyl)oxazole

Image non disponible-BOSSBS-7571R-HRP

Anti-RPS3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-7571R-HRP)
Fournisseur: Bioss
Description: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7571R-A555

Anti-RPS3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-7571R-A555)
Fournisseur: Bioss
Description: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).
UOM: 1 * 100 µl
Image non disponible-BSBTA01672-1

Anti-UNG Rabbit Polyclonal Antibody

Numéro de catalogue: (BSBTA01672-1)
Fournisseur: Boster Bio
Description: Rabbit IgG polyclonal antibody for Uracil-DNA glycosylase(UNG) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
UOM: 1 * 1 EA
Image non disponible-6680-25

Uridine, Millipore®

Fournisseur: Merck Millipore (Calbiochem‎)
Description: Uridine, Millipore®

Image non disponible-APOSOR2054-5G

2-(Chloromethyl)tetrahydropyran 99%

Numéro de catalogue: (APOSOR2054-5G)
Fournisseur: Apollo Scientific
Description: 2-(Chloromethyl)tetrahydropyran 99%
UOM: 1 * 5 g
Image non disponible-PRSI92-122

Human recombinant uridine phosphorylase 1 (from E. coli)

Numéro de catalogue: (PRSI92-122)
Fournisseur: ProSci Inc.
Description: Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.
UOM: 1 * 50 µG
Image non disponible-BOSSBS-7571R-A750

Anti-RPS3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-7571R-A750)
Fournisseur: Bioss
Description: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerisation (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).
UOM: 1 * 100 µl
Image du produit-ACRO391150100

4-(Chloromethyl)benzonitrile 98%

Fournisseur: Thermo Fisher Scientific
Description: 4-(Chloromethyl)benzonitrile 98%

MSMD

Image non disponible-J64147.06

1-β-D-Arabinofuranosyluracil 99%

Fournisseur: Thermo Fisher Scientific
Description: 1-β-D-Arabinofuranosyluracil 99%

MSMD Certificats

Image non disponible-APOSOR957448-5G

3-(Chloromethyl)phenol 95%

Fournisseur: Apollo Scientific
Description: 3-(Chloromethyl)phenol 95%

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