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Anti-MCT1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-10249R-A750)

Fournisseur: Bioss

Description: Proton-coupled monocarboxylate transporter. catalyses the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on circumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

UOM: 1 * 100 µl

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Anti-SLC5A8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-6106R-HRP)

Fournisseur: Bioss

Description: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.

UOM: 1 * 100 µl

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Acide naphtyl-2 acétique

Numéro de catalogue: (MOLE12224581-5G)

Fournisseur: Molekula

Description: Acide naphtyl-2 acétique

UOM: 1 * 5 g

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Human Recombinant TGF-beta 1 (Cell Culture Ready)

Numéro de catalogue: (STMC100-0856)

Fournisseur: STEMCELL Technologies

Description: Conveniently and consistently add transforming growth factor beta 1 (TGF-ꞵ1) to your cultures with this cell culture-ready formulation. This human recombinant TGF-ꞵ1 is precisely reconstituted to 0,1 mg/ml in 100 mM acetic acid and requires no additional preparation, improving reproducibility. Endotoxin levels are verified, using the LAL method to ensure consistency for use across multiple applications. A member of the TGF-β superfamily, TGF-β1 regulates diverse cellular phenotypes. TGF-β1 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins.

UOM: 1 * 1 mL

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Anti-SLC16A8 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI29-925)

Fournisseur: ProSci Inc.

Description: SLC16A8 is proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

UOM: 1 * 1 EA

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Anti-SLC16A6 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI25-901)

Fournisseur: ProSci Inc.

Description: SLC16A6 is a proton-linked monocarboxylate transporter.It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

UOM: 1 * 50 µG

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EGTA (Acide éthylèneglycol bis-(amino-2-éthyléther) N,N,N'N'-tétraacétique) ≥98%, poudre cristalline blanche

Fournisseur: MP Biomedicals

Description: Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent. It is an inhibitor of alkaline phosphatase activity which is useful in ELISA reactions.

Anti-HCAR2 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI56-577)

Fournisseur: ProSci Inc.

Description: NIACR1 acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.

UOM: 1 * 400 µl

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