Votre recherche pour: WLD-TEC+GmbH

Numéro de catalogue: (ABNOMAB6482)

Fournisseur: Abnova

Description: Mouse monoclonal antibody raised against Plscr1.

UOM: 1 * 100 µl

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Fournisseur: ELMA SCHMIDBAUER

Description: Powerful cleaners for ultrasonic baths suitable for many industrial cleaning tasks

Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Évaporateur, rotatif

Numéro de catalogue: (BOSSBS-0113R-CY5)

Fournisseur: Bioss

Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway.

UOM: 1 * 100 µl

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Numéro de catalogue: (BOSSBS-0113R-A488)

Fournisseur: Bioss

Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway.

UOM: 1 * 100 µl

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Fournisseur: WELLS LAMONT

Description: Doublures de gants stériles et jetables résistantes aux coupures.

Fournisseur: JULABO GmbH

Description: Bain-marie

Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Supports réducteurs

Numéro de catalogue: (HEID23-30-01-04-88)

Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Centering ring

UOM: 1 * 1 ST

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Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Flat hood

Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Évaporateur rotatif

Numéro de catalogue: (217-0695)

Fournisseur: Lenz Laborglas GmbH & CO.KG

Description: Pulvérisateur en verre borosilicaté DURAN®.

UOM: 1 * 1 ST

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Fournisseur: THARMAC GmbH

Description: Adaptateur de rotor amovible

Fournisseur: Heidolph Instruments GmbH & Co.KG

Description: Évaporateur, rotatif

Fournisseur: MOTIC

Description: The Panthera TEC POL models present a high flexibility for the inspection of all kind of polarizing materials, for transparent samples like fibers and foils with their inherent birefringence, as well as for opaque specimen from education environment and industrial quality control.

Numéro de catalogue: (BOSSBS-2752R-CY5)

Fournisseur: Bioss

Description: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

UOM: 1 * 100 µl

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