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Image non disponible-BOSSBS-0244R-FITC

Anti-HSPA1A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-0244R-FITC)
Fournisseur: Bioss
Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
UOM: 1 * 100 µl
Image non disponible-BNUB0872-100

Anti-RBP1 Mouse Monoclonal Antibody (Purified) [clone: RBP/872]

Fournisseur: Biotium
Description: Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

Image du produit-432-0214

VWR®, Broyeurs de tissus, type Potter-Elvehjem

Fournisseur: VWR Collection
Description: Tube en verre borosilicaté, pilon en PTFE avec tige en acier inoxydable. Les broyeurs de tissus sont utilisés pour réduire de manière contrôlée la taille des particules et homogénéiser une large gamme de substances, notamment biologiques. Les forces de cisaillement générées par le mouvement de rotation du piston dans le tube calibré entraînent une réduction de la taille. Les facteurs déterminants étant l'espace entre la tête du pilon et le tube, la vitesse de rotation et la viscosité du milieu.

Image du produit-1.15092.1000

Extraction liquide-liquide, Extrelut® NT

Fournisseur: Merck
Description: Extrelut® NT est une terre silicieuse de structure granulaire avec un volume de pores élevé. Il a démontré son efficacité en chimie clinique et en toxicologie pour la préparation d'échantillons d'urine, de sang, de plasma et autres matrices biologiques. D'autres applications sont les analyses environnementales et de résidus des eaux usées industrielles ou domestiques. Extrelut® NT est livré en cartouches pré-remplies ou sous forme d'adsorbant en vrac. Ses propriétés de surface permettent une action comme support pour l'extraction liquide-liquide de substances lipophiles au lieu d'utiliser une ampoule à décanter. Lorsqu'un échantillon aqueux est appliqué sur l'adsorbant Extrelut® NT, il se répartit en un film fin sur la surface et agit comme une phase stationnaire. L'élution des analytes s'obtient en utilisant un solvant organique non miscible avec l'eau, comme l'éther diéthylique, de l'acétate d'éthyle ou des hydrocarbures halogénés.

MSMD

Image non disponible-BOSSBS-12402R-CY5

Anti-RBM15 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-12402R-CY5)
Fournisseur: Bioss
Description: RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12402R-A680

Anti-RBM15/SPEN Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-12402R-A680)
Fournisseur: Bioss
Description: RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukaemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12402R-HRP

Anti-RBM15 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-12402R-HRP)
Fournisseur: Bioss
Description: RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-8870R-A647

Anti-HAMP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-8870R-A647)
Fournisseur: Bioss
Description: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9671R-A750

Anti-ASH1L Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-9671R-A750)
Fournisseur: Bioss
Description: ASH1L is a 2969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3840R-A350

Anti-EIF3A Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-3840R-A350)
Fournisseur: Bioss
Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9671R-CY3

Anti-ASH1L Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-9671R-CY3)
Fournisseur: Bioss
Description: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-4916R-CY3

Anti-CD44 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-4916R-CY3)
Fournisseur: Bioss
Description: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-4916R-CY5.5

Anti-CD44 Rabbit Polyclonal Antibody (Cy5.5®)

Numéro de catalogue: (BOSSBS-4916R-CY5.5)
Fournisseur: Bioss
Description: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-2780R-CY5

Anti-CD44 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-2780R-CY5)
Fournisseur: Bioss
Description: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3826R-A680

Anti-Histone H4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-3826R-A680)
Fournisseur: Bioss
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3186R-A647

Anti-HIST3H3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-3186R-A647)
Fournisseur: Bioss
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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