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Image du produit-PRSI4979

Anti-RNASEH2A Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI4979)
Fournisseur: ProSci Inc.
Description: RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
UOM: 1 * 1 EA
Image du produit-E521-100ML

Sodium acétate Solution tampon pH 5,2 (3 mol/L), traitement au DEPC,

Numéro de catalogue: (E521-100ML)
Fournisseur: VWR Chemicals
Description: With diethyl pyrocarbonate (DEPC).
UOM: 1 * 100 mL

MSMD Certificats


Image non disponible-BOSSBS-3969R-A680

Anti-PRKAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-3969R-A680)
Fournisseur: Bioss
Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed.
UOM: 1 * 100 µl
Image non disponible-TCIAM0707-250G

Acide γ-morpholinopropanesulfonique (MPOS) ≥98.0% (par analyse titrimétrique) composant de tampon pour la recherche biologique

Fournisseur: TCI
Description: Acide γ-morpholinopropanesulfonique (MPOS) ≥98.0% (par analyse titrimétrique) composant de tampon pour la recherche biologique

Image non disponible-BOSSBS-3969R-A350

Anti-PRKAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-3969R-A350)
Fournisseur: Bioss
Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3969R-A750

Anti-PRKAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-3969R-A750)
Fournisseur: Bioss
Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed.
UOM: 1 * 100 µl
Image non disponible-J62204.AP

IEF Cathode buffer (10X) with lysine and arginine

Numéro de catalogue: (J62204.AP)
Fournisseur: Thermo Fisher Scientific
Description: Tampon de migration, IEF Cathode buffer (10X) with lysine and arginine
UOM: 1 * 500 mL

MSMD Certificats


Image du produit-PRSI79-407

Anti-IGF1R Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI79-407)
Fournisseur: ProSci Inc.
Description: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
UOM: 1 * 1 EA
Image non disponible-BOSSBS-0890R-A680

Anti-GFP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-0890R-A680)
Fournisseur: Bioss
Description: Green fluorescence protein (GFP) is a 27 kDa protein derived from the jellyfish Aequorea victoria, which emits green light (emission peak at a wavelenth of 509 nm) when excited by blue light (excitation peak at a wavelenth of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell biology research, since its intrinsic fluorescence can be visualized in living cells. GFP fluorescence is stable under fixation conditions and suitable for a variety of applications. GFP has been widely used as a reporter for gene expression, enabling researchers to visualize and localize GFP-tagged proteins within living cells without the need for chemical staining. Other applications of GFP include assessment of protein protein interactions through the yeast two hybrid system and measurement of distance between proteins through fluorescence energy transfer (FRET) protocols. GFP technnology has considerably contributed to a greater understanding of cellular physiology.
UOM: 1 * 100 µl
Image du produit-115-1752

Tampons manuels, ultra fins, 7448, Scotch-Brite™

Numéro de catalogue: (115-1752)
Fournisseur: 3M
Description: Fabriqué en toile confortable, ce tampon est le tampon à main en carbure de silicium le plus fin du marché. Il est parfait pour les travaux de nettoyage léger et de finitions, et peut être utilisé à la main, avec un bloc tampon manuel ou sur une ponceuse électrique.
UOM: 1 * 20 ST
Image du produit-BSBTPB10000

Anti-DDAH1 Rabbit Polyclonal Antibody

Numéro de catalogue: (BSBTPB10000)
Fournisseur: Boster Bio
Description: DDAH1 is knowns as dimethylarginine dimethylaminohydrolase 1 which is mapped to chromosome 1p22 by radiation hybrid and FISH analysis. This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. DDAH1 plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. It widely expressed, especially in liver and kidney.
UOM: 1 * 1 EA
Image du produit-BARN88882014

Thermo Scientific™ Digital Platform Rocker

Numéro de catalogue: (BARN88882014)
Fournisseur: Thermo Fisher Scientific
Description: The Thermo Scientific™ Digital platform rockers provide gentle motion for mixing samples. Designed for hybridization, blotting and staining or distaining gels.
UOM: 1 * 1 ST
Image du produit-18-3216-03

Accessoires pour systèmes de chromatographie

Numéro de catalogue: (18-3216-03)
Fournisseur: Cytiva
Description: Réservoir de tampon LabMate PD-10
UOM: 1 * 10 ST
Image non disponible-WATE186005406

UPLC columns, ACQUITY UPLC™ CSH phenyl-hexyl

Numéro de catalogue: (WATE186005406)
Fournisseur: WATERS
Description: These columns provides complementary selectivity to straight-chain-alkyl phases, particularly for polyaromatic compounds. Built on Charged Surface Hybrid (CSH) particle platform.
UOM: 1 * 1 ST

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Image du produit-118-0480

Flacons de solution de lavage oculaire, Duo

Fournisseur: Plum Safety
Description: Solution de chlorure de sodium 0,9% stérile. Pour les blessures dues à des corps étrangers tels que la poussière, la saleté, etc. Solution tampon phosphate stérile 4,9% pour neutraliser les acides et les alcalis.

Certificats

Image non disponible-BOSSBS-3969R-A647

Anti-PRKAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-3969R-A647)
Fournisseur: Bioss
Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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