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Image non disponible-BOSSBS-12477R-CY7

Anti-ANXA11 Rabbit Polyclonal Antibody (Cy7®)

Description: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
Numéro de catalogue: BOSSBS-12477R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-5751R-A350

Anti-MATK Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Numéro de catalogue: BOSSBS-5751R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-4307R-CY7

Anti-DEFB4A Rabbit Polyclonal Antibody (Cy7®)

Description: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways
Numéro de catalogue: BOSSBS-4307R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image du produit-630-1635

VWR® VisiScope®, Accessoires

Description: Accessoire, VWR® VisiScope®, Kit de polarisation (filtres uniquement)
Numéro de catalogue: 630-1635
UOM: 1 * 1 ST
Fournisseur: VWR Collection
Image du produit-BURK7109-0050

Béchers triangulaires, à usage unique

Description: PP, translucent.
Numéro de catalogue: BURK7109-0050
UOM: 1 * 1 ST
Fournisseur: BURKLE
Image non disponible-BOSSBS-8053R-HRP

Anti-KLHL3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Numéro de catalogue: BOSSBS-8053R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-ENZOADIKAPST002C

Anti-GSK3B Rabbit Polyclonal Antibody

Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.
Numéro de catalogue: ENZOADIKAPST002C
UOM: 1 * 25 µG
Fournisseur: ENZO LIFE SCIENCES
Image non disponible-ENZOADI905762100

Anti-GSK3A Mouse Monoclonal Antibody [clone: 6D3]

Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.
Numéro de catalogue: ENZOADI905762100
UOM: 1 * 1 EA
Fournisseur: ENZO LIFE SCIENCES
Image non disponible-BOSSBS-1393R-A750

Anti-Jun D Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
Numéro de catalogue: BOSSBS-1393R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1393R-A555

Anti-Jun D Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
Numéro de catalogue: BOSSBS-1393R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1393R-HRP

Anti-Jun D Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Description: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
Numéro de catalogue: BOSSBS-1393R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1912R-FITC

Anti-HCG alpha Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
Numéro de catalogue: BOSSBS-1912R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1912R-A488

Anti-HCG alpha Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
Numéro de catalogue: BOSSBS-1912R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1471R-CY7

Anti-Annexin VI Rabbit Polyclonal Antibody (Cy7®)

Description: The Annexin family of calcium binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.
Numéro de catalogue: BOSSBS-1471R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1471R-CY5.5

Anti-Annexin VI Rabbit Polyclonal Antibody (Cy5.5®)

Description: The Annexin family of calcium binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.
Numéro de catalogue: BOSSBS-1471R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image du produit-111-2511

Bouchons d'oreille réutilisables, ajustement flexible, E-A-R™

Description: E-A-R™ Flexible Fit HA earplugs have a patented earplug foam formulation which makes them fully washable and reusable. The soft foam tip and flexible fitting stem allows easy insertion into the ear using one or two hands, as the foam tip conforms to the unique shape of the ear canal to help block out noise. These earplugs are ideal for activities that require gloves or cause dirty hands, or situations when only one hand is free to fit the earplugs.
Numéro de catalogue: 111-2511
UOM: 1 * 500 PAIRE
Fournisseur: 3M
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