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Image non disponible-BOSSBS-11784R-A488

Anti-SPR Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-11784R-A488)
Fournisseur: Bioss
Description: SPR, also known as sepiapterin reductase, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family. SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives. In addition, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the final reduction step of the synthesis pathway. BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine) and is required for proper dopamine synthesis. Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, a monoamine neurotransmitter deficiency without hyperphenylalaninemia. Sepiapterin reductase deficiency interferes with BH4 synthesis, resulting in DOPA-responsive dystonia and a variety of other human diseases. In addition, SPR mRNA expression is increased in the brain of Parkinson’s Disease (PD) patients, suggesting that SPR may play a role in PD.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11784R-HRP

Anti-SPR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-11784R-HRP)
Fournisseur: Bioss
Description: SPR, also known as sepiapterin reductase, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family. SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives. In addition, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the final reduction step of the synthesis pathway. BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine) and is required for proper dopamine synthesis. Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, a monoamine neurotransmitter deficiency without hyperphenylalaninemia. Sepiapterin reductase deficiency interferes with BH4 synthesis, resulting in DOPA-responsive dystonia and a variety of other human diseases. In addition, SPR mRNA expression is increased in the brain of Parkinson’s Disease (PD) patients, suggesting that SPR may play a role in PD.
UOM: 1 * 100 µl
Image non disponible-MOLE20706773-25G

N(α)-Cbz-L-tryptophan

Numéro de catalogue: (MOLE20706773-25G)
Fournisseur: Molekula
Description: N(α)-Cbz-L-tryptophan
UOM: 1 * 25 g

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Image non disponible-BOSSBS-6659R-CY5

Anti-SLC3A2 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-6659R-CY5)
Fournisseur: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6659R-A750

Anti-CD98 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-6659R-A750)
Fournisseur: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarised intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6659R-A555

Anti-SLC3A2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-6659R-A555)
Fournisseur: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl
Image non disponible-399698-25

5-Hydroxy-L-tryptophane, Millipore®

Numéro de catalogue: (399698-25)
Fournisseur: Merck Millipore (Calbiochem‎)
Description: 5-Hydroxy-L-tryptophane, Millipore®
UOM: 1 * 25 g
Image non disponible-6540-100

L(-)-Tryptophane, Millipore®

Numéro de catalogue: (6540-100)
Fournisseur: Merck Millipore (Calbiochem‎)
Description: L(-)-Tryptophane, Millipore®
UOM: 1 * 100 g
Image non disponible-ICNA0210315191

L(-)-Tryptophane ≥99%, en poudre

Fournisseur: MP Biomedicals
Description: L-Tryptophan is an amino acid precursor of serotonin and melatonin.

Image non disponible-L17671.MD

DL-2-Amino-4-phosphonobutyric acid 95%

Numéro de catalogue: (L17671.MD)
Fournisseur: Thermo Fisher Scientific
Description: DL-2-Amino-4-phosphonobutyric acid 95%
UOM: 1 * 250 mg

MSMD Certificats


Image non disponible-APOSPC1076DC-250MG

DL-4-Amino-2-fluorobutyric acid 99%

Numéro de catalogue: (APOSPC1076DC-250MG)
Fournisseur: Apollo Scientific
Description: DL-4-Amino-2-fluorobutyric acid 99%
UOM: 1 * 250 mg
Image non disponible-8.07020.1000

(±)-1-Amino-2-propanol mélange d'isomères ≥98% pour la synthèse, Sigma-Aldrich®

Fournisseur: Merck
Description: Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

MSMD

Image non disponible-APOSOR906370-5G

2-Amino-N-methyl-DL-propanamide 98%

Fournisseur: Apollo Scientific
Description: 2-Amino-N-methyl-DL-propanamide 98%

Image non disponible-APOSOR962733-5G

DL-3-(BOC-Amino)-1-butanol 97%

Fournisseur: Apollo Scientific
Description: DL-3-(BOC-Amino)-1-butanol 97%

Image non disponible-TCIAA1003-5G

DL-ɑ-Amino-ε-caprolactam ≥98.0% (par GC)

Fournisseur: TCI
Description: DL-ɑ-Amino-ε-caprolactam ≥98.0% (par GC)

Image non disponible-APOSBIT0723-1KG

DL-Tyrosine

Numéro de catalogue: (APOSBIT0723-1KG)
Fournisseur: Apollo Scientific
Description: DL-Tyrosine
UOM: 1 * 1 kg
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