Votre recherche pour: Tonbo Biosciences

Fournisseur: Tonbo Biosciences

Description: The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO. The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Numéro de catalogue: (72-8107-U500)

Fournisseur: Tonbo Biosciences

Description: Goat anti-Human Kappa (к) Light Chain - Affinity Pure, HRP Conjugate

UOM: 1 * 0,5 mg

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Numéro de catalogue: (72-8112-M001)

Fournisseur: Tonbo Biosciences

Description: Goat anti-Human IgG + IgA + IgM - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

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Fournisseur: Tonbo Biosciences

Description: The HIT2 antibody is specific for human CD38, a 45 kD type II transmembrane glycoprotein expressed on thymocytes, activated T and B cells, and monocytes as well as other non-hematopoietic cells. CD38 is an ectoenzyme that functions to catalyse the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases

Fournisseur: Tonbo Biosciences

Description: The UCHT2 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein, that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is involved in modulating antigen receptor signalling in both T and B cells and binds to CD72, expressed on B cells.

Numéro de catalogue: (65-0459-T025)

Fournisseur: Tonbo Biosciences

Description: The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

UOM: 1 * 25 Tests

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Numéro de catalogue: (35-8054-U500)

Fournisseur: Tonbo Biosciences

Description: Goat anti-Mouse IgG (H&L), F(ab')2 Fragment - Affinity Pure, FITC Conjugate

UOM: 1 * 0,5 mg

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Numéro de catalogue: (35-8064-M002)

Fournisseur: Tonbo Biosciences

Description: Goat anti-Mouse IgM (H&L) - Affinity Pure, FITC Conjugate

UOM: 1 * 2 mg

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Numéro de catalogue: (72-8094-M001)

Fournisseur: Tonbo Biosciences

Description: Donkey anti-Sheep IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

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Numéro de catalogue: (70-8037-U500)

Fournisseur: Tonbo Biosciences

Description: Donkey anti-Rabbit IgG (H&L), F(ab')2 Fragment- Affinity Pure, min x w/ Bovine, Chicken, Goat, Guinea Pig, Hamster, Horse, Human, Mouse, Rat or Sheep

UOM: 1 * 0,5 mg

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Numéro de catalogue: (35-8081-M002)

Fournisseur: Tonbo Biosciences

Description: Goat anti-Chicken IgY (H&L) - Affinity Pure, FITC Conjugate

UOM: 1 * 2 mg

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Fournisseur: Tonbo Biosciences

Description: The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB and CD45RO.

Fournisseur: Tonbo Biosciences

Description: The OKT4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Numéro de catalogue: (80-4321-U100)

Fournisseur: Tonbo Biosciences

Description: The 2A3 immunoglobulin is useful as an isotype-matched control. The 2A3 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2a antibodies.

UOM: 1 * 1 EA

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Fournisseur: Tonbo Biosciences

Description: The Mouse Dendritic Cell backbone panel is a six-color combination of anti-mouse antibodies. This panel can serve as a backbone for identifying major dendritic cell (DC) subsets (Duriancik DM and Hoag KA. 2009. Cytometry. 75A: 951-959). Hosts: Rat, Armenian Hamster

Fournisseur: Tonbo Biosciences

Description: The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.