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Votre recherche pour: Acide+alginique


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Description: 2'-Fluoro NTPs are being utilised in an increasing number of applications in research and new drug development. 2'-Fluoro-dUTP is incorporated in both DNA and RNA constructs to improve <em>in vivo</em> stability.
Numéro de catalogue: SOLUN-1010-5
UOM: 1 * 5 µmol
Fournisseur: TriLink BioTechnologies

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Description: Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
Numéro de catalogue: ENZOBMLFA0180050
UOM: 1 * 50 mg
Fournisseur: ENZO LIFE SCIENCES


Description: Potent inhibitor of insulin-like growth factor I receptor (IGF-IR) signalling and breast cancer cell growth in culture and in vivo.
Numéro de catalogue: ENZOALX270459M005
UOM: 1 * 5 mg
Fournisseur: ENZO LIFE SCIENCES


Description: Inhibitory iODN oligodeoxynucleotide with phosphorothioate backbone. Sequence of an inhibitory ODN for in vivo use in rodents (50-150µg per injection): prototype class I that potently inhibits TLR9 and TLR7 signaling.
Numéro de catalogue: ENZOALX746255C100
UOM: 1 * 1 EA
Fournisseur: ENZO LIFE SCIENCES


Description: Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions <i>in vivo</i>. Rosiglitazone is a prototypical TZD and has served as a reference compound for this class. Rosiglitazone is a potent and selective PPARγ ligand. It binds to the PPARγ ligand-binding domain with a Kd of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC<sub>50</sub> values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active <i>in vivo</i> as an antidiabetic agent in the <i>ob/ob</i> mouse model, and has been used as an oral hypoglycemic agent in the treatment of Type II diabetes in humans for many years.
Numéro de catalogue: CAYM71740-10
UOM: 1 * 10 mg
Fournisseur: Cayman Chemical


Description: Formalin solution, neutral buffered, 10% is the most commonly used fixative for light microscopy. It requires a relatively short period of fixation. It is suitable for the long-term storage of tissue. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining. 10% NBF is well suited for large throughput laboratories, and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue. Formalin fixation is thought to form between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their <i>in vivo</i> relationship.
Numéro de catalogue: HT501640-19L
UOM: 1 * 19 L
Fournisseur: SIGMA ALDRICH MICROSCOPY


Description: Highly selective plasma kallikrein inhibitor (Ki = 0.81 µM). Can be used for affinity purification of kalikrein. Suppresses collagen-induced arthritis in a mouse model. Synergizes with NO donors producing antithrombotic effects ex vivo.
Numéro de catalogue: ENZOBMLPI1470005
UOM: 1 * 5 mg
Fournisseur: ENZO LIFE SCIENCES


Description: Water soluble, used in sandwich ELISAs and in In Vivo tumor site localisationRef: Suter.M & Butler J.E (1986) Immunology letters 13, 313-316
Numéro de catalogue: APOSBIB103-100MG
UOM: 1 * 100 mg
Fournisseur: Apollo Scientific


Description: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Numéro de catalogue: BOSSBS-1755R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.
Numéro de catalogue: 40-7102-U500
UOM: 1 * 500 µG
Fournisseur: Tonbo Biosciences


Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
Numéro de catalogue: BOSSBS-4123R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: PAF receptor antagonist. Inhibits PAF-induced human platelet and neutrophil aggregation in vitro (IC50=0.17 and 0.36µM respectively). In vivo it dose dependently blocks eosinophil activation and displays antiallergic and anti-inflammatory activity in various models. Induces differentiation and triggers apoptosis and in a variety of cell lines.
Numéro de catalogue: ENZOBMLL1370005
UOM: 1 * 5 mg
Fournisseur: ENZO LIFE SCIENCES


Description: The implantation of individual micro-dialysis hollow fibers is an ideal step in the recovery or introduction of micro-quantity biologicals or pharmaceutical materials in a localized tissue environment. Following sample injection into the lumen via syringe, the fiber ends may be sealed with epoxy for implantation.
Numéro de catalogue: SPEC132294
UOM: 1 * 20 ST
Fournisseur: Spectrum Laboratories


Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Numéro de catalogue: BOSSBS-1303R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Numéro de catalogue: BOSSBS-1303R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
Numéro de catalogue: BOSSBS-4123R
UOM: 1 * 100 µl
Fournisseur: Bioss


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