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Petunidin chloride ≥98%

Fournisseur: Cayman Chemical

Description: Petunidin is an O-methylated anthocyanidin derived from delphinidin that imparts blue-red pigments to flowers, fruits, and red wine. Used to bind with and suppress the activity of focal adhesion kinase and to inhibit platelet-derived growth factor-induced aortic smooth muscle cell migration, which may confer a protective effect against atherosclerosis. Extracts from E. jambolana fruit, which is rich in anthocyanins including petunidin, have been used to suppress the proliferation of an HCT116 colon cancer cell line, as well as colon cancer stem cells.

4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulphonic acid dipotassium salt ≥98%, solide cristallin colorant fluorescent

Fournisseur: Cayman Chemical

Description: bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation. Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.

Purvalanol A ≥98%, solide cristallin

Fournisseur: Cayman Chemical

Description: Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

5-Fluoro-2'-deoxyuridine (Floxuridine)

Fournisseur: Cayman Chemical

Description: 5-Fluoro-2'-deoxyuridine (Floxuridine)

N-Octyle β-D-Glucopyrannoside

Fournisseur: Cayman Chemical

Description: N-Octyle β-D-Glucopyrannoside

Doxorubicin hydrochloride ≥98%

Fournisseur: Cayman Chemical

Description: Doxorubicin is an anthracycline anti-tumour antibiotic which involves in inhibition of DNA topoisomerase II by inducing double-stranded DNA breaks. It is also involved in the inhibition of nucleic acid synthesis by intercalating within DNA. The accumulation of the p53 tumour suppressor protein leads to the apoptosis in cells.

6-Cyano-7-nitroquinoxaline-2,3-dione ≥98%

Fournisseur: Cayman Chemical

Description: CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors).
This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.

Anti-Nitrotyrosine Rabbit Polyclonal Antibody

Numéro de catalogue: (CAYM10006778-500)

Fournisseur: Cayman Chemical

Description: Anti-Nitrotyrosine Rabbit Polyclonal Antibody

UOM: 1 * 500 µl

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Glycyrrhetic acid ≥98%

Fournisseur: Cayman Chemical

Description: 18β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC<sub>50</sub> = 35 μM). At 100 mg/kg/day, 18β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. It inhibits mammalian DNA polymerases α, γ, κ and λ with IC<sub>50</sub> values of 16,1, 19,3, 15,8 and 13,7 μM, respectively. At 100-200 μM, 18β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

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