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Image non disponible-BOSSBS-6625R

Anti-INSIG2 Rabbit Polyclonal Antibody

Numéro de catalogue: (BOSSBS-6625R)
Fournisseur: Bioss
Description: Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
UOM: 1 * 100 µl
Image du produit-633-0227

Colorimètres spectrophotométriques, série Lovibond® PFXi 880

Fournisseur: Lovibond Tintometer
Description: Une série de colorimètres spectrophotométriques automatiques pour l'analyse objective de la couleur des huiles alimentaires, des produits chimiques, des produits pétrochimiques, des carburants et d'autres produits transparents. Les instruments PFX<i>i</i><i> </i>880 sont des colorimètres robustes avec des boîtiers en acier, qui fonctionnent également en tant qu'instruments QC dans les laboratoires ou en fonctionnement continu dans un environnement de production. La précision et la reproductibilité des données colorimétriques fournies par ces colorimètres garantissent l'uniformité dans la mesure des couleurs, donnant aux opérateurs la confiance requise pour prendre d'importantes décisions concernant les matières premières et les opérations de raffinage.

Image du produit-710-0736

Stérilisateur de milieu nutritif, MediaClave 30

Numéro de catalogue: (710-0736)
Fournisseur: BDP International Inc.
Description: Le stérilisateur de milieux de culture MediaClave 30, qui permet de fabriquer de 3 à 30 l de milieu nutritif, est un appareil mobile innovant pour la production fiable de milieux de culture aux exigences haut de gamme. Il intègre une technologie de pointe, mais reste simple d'utilisation, ce qui le rend particulièrement adapté aux types de gélose standard et aux milieux à haute sensibilité. Le système de chauffage à flux continu efficace et innovant, l'agitateur magnétique puissant et le processus de refroidissement rapide garantissent la stérilisation sécurisée et homogène des milieux aux températures requises. Le MediaClave 30 est conforme aux dernières exigences pour la documentation de l'appareil et bien sûr aux normes GMP/GLP et FDA CFR 21 Part 11. Avec programme de nettoyage automatique et processus de refroidissement rapide d'une grande efficacité.
UOM:


Image du produit-BRDY311937

Brady® FR22 RFID Fixed Reader

Numéro de catalogue: (BRDY311937)
Fournisseur: Brady
Description: The BRADY FR22 is the core device of a new approach for RFID fixed systems with wide communication options and a modular design. The FR22 is a critical building block for various track and trace and intelligent manufacturing solutions. It enables different use cases for different segments depending on which modules are attached to it.
UOM: 1 * 1 ST
Image non disponible-BOSSBS-1235R-CY5

Anti-HYAL1 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-1235R-CY5)
Fournisseur: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9051R-A350

Anti-TRPM4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-9051R-A350)
Fournisseur: Bioss
Description: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9051R-CY5

Anti-TRPM4 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-9051R-CY5)
Fournisseur: Bioss
Description: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12215R-CY3

Anti-ZNF266 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-12215R-CY3)
Fournisseur: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1049R-A488

Anti-CHRNA7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-1049R-A488)
Fournisseur: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-8191R-A555

Anti-CPPED1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-8191R-A555)
Fournisseur: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-8191R-A647

Anti-CPPED1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-8191R-A647)
Fournisseur: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-8191R-HRP

Anti-CPPED1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-8191R-HRP)
Fournisseur: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12215R-A680

Anti-ZNF266 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-12215R-A680)
Fournisseur: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Kr_ppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
UOM: 1 * 100 µl
Image non disponible-BNUM0988-50

Anti-ICAM1 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: 1H4 or Wehi-CAM-1 or W-CAM-1]

Numéro de catalogue: (BNUM0988-50)
Fournisseur: Biotium
Description: Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).
UOM: 1 * 50 µl
Image non disponible-BOSSBS-5161R-CY7

Anti-CAPZA1 Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-5161R-CY7)
Fournisseur: Bioss
Description: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6675R-CY5

Anti-KCNN4 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-6675R-CY5)
Fournisseur: Bioss
Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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