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Description: AKIRIN1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the transcription of NF-kB dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways.

Numéro de catalogue: BOSSBS-9081R

UOM: 1 * 100 µl

Fournisseur: Bioss

Promotion

Description: Anti-AKIRIN2 Mouse Monoclonal Antibody [clone: 3D9]

Numéro de catalogue: USBI123150

UOM: 1 * 1 EA

Fournisseur: US Biological

Promotion

Description: Akirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappa B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappa B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1 beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.

Numéro de catalogue: PRSI4805

UOM: 1 * 1 EA

Fournisseur: ProSci Inc.

Promotion

Description: Akirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappa B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappa B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1 beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.

Numéro de catalogue: PRSI4803

UOM: 1 * 1 EA

Fournisseur: ProSci Inc.

Promotion

Description: Akirin1 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappa B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappa B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1 beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.

Numéro de catalogue: PRSI4799

UOM: 1 * 1 EA

Fournisseur: ProSci Inc.

Promotion

Description: Akirin1 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappa B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappa B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1 beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.

Numéro de catalogue: PRSI4801

UOM: 1 * 1 EA

Fournisseur: ProSci Inc.

Promotion

Description: ORF CLONE HUMAN NM_018064 1 * 10 µG

Numéro de catalogue: ORIGRC200881

UOM: 1 * 1 EA

Fournisseur: OriGene

Promotion

Description: Anti-AKIRIN1 Rabbit Polyclonal Antibody

Numéro de catalogue: USBI031737

UOM: 1 * 200 µl

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN2 Rabbit Polyclonal Antibody (Biotin)

Numéro de catalogue: USBI031738-BIOTIN

UOM: 1 * 200 µl

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN2 Rabbit Polyclonal Antibody

Numéro de catalogue: USBI031738

UOM: 1 * 200 µl

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN1 Rabbit Polyclonal Antibody

Numéro de catalogue: USBIA1105-80D

UOM: 1 * 50 µG

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN2 Rabbit Polyclonal Antibody

Numéro de catalogue: AVIVARP66510_P050

UOM: 1 * 50 µG

Fournisseur: Aviva Systems Biology

Promotion

Description: Anti-AKIRIN1 Rabbit Polyclonal Antibody

Numéro de catalogue: USBIA1105-80C

UOM: 1 * 50 µG

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN1 Rabbit Polyclonal Antibody

Numéro de catalogue: USBIA1105-80

UOM: 1 * 1 EA

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN2 Rabbit Polyclonal Antibody

Numéro de catalogue: USBIA1105-81C

UOM: 1 * 50 µG

Fournisseur: US Biological

Promotion

Description: Anti-AKIRIN2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Numéro de catalogue: USBI031738-PE

UOM: 1 * 200 µl

Fournisseur: US Biological

Promotion