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Image non disponible-BOSSBS-13536R-CY5

Anti-FFAR2 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-13536R-CY5)
Fournisseur: Bioss
Description: G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13536R-A350

Anti-FFAR2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-13536R-A350)
Fournisseur: Bioss
Description: G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13536R-HRP

Anti-FFAR2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-13536R-HRP)
Fournisseur: Bioss
Description: G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13536R-A488

Anti-FFAR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-13536R-A488)
Fournisseur: Bioss
Description: G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
UOM: 1 * 100 µl
Image du produit-REST22062

Gas trapping systems for LC/MS, Super Clean®

Numéro de catalogue: (REST22062)
Fournisseur: Restek
Description: The Super Clean® gas trapping system purifies nitrogen and is ideal for use in LC-MS systems. The two position base plate (installed in the gas line; standard base plate inlet/outlet fittings accept ¹/₄" tubing) allows cartridges to be exchanged without introducing impurities into the system. To meet the high flow needs of the LC-MS system, the activated charcoal filled cartridges are positioned and connected in parallel.
UOM: 1 * 1 KIT
Image du produit-BSENM-1738-100

Anti-NGF Mouse Monoclonal Antibody [clone: BS312]

Numéro de catalogue: (BSENM-1738-100)
Fournisseur: Biosensis
Description: Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.
UOM: 1 * 1 EA
Image du produit-442-0976

Systèmes de blocs de réaction pour agitateurs magnétiques à plaque chauffante RH basic, RH digital, RCT basic, RET basic et RET control-visc

Fournisseur: IKA
Description: Les blocs de réaction permettent d'effectuer des synthèses dans des flacons à fond rond à des températures pouvant atteindre jusqu'à 180 ˚C, évitant ainsi le recours à des bains d'huile. Le système assure un transfert thermique optimal depuis la plaque chauffante, directement dans le milieu. Il garantit également un mélange uniforme grâce à l'absence d'interférences avec le champ magnétique des blocs en aluminium. Les blocs de réaction sont proposés dans des volumes allant de 100 à 5000 ml. Des inserts accueillant des flacons à fond rond de 10 à 3000 ml sont également disponibles. Grâce à sa gamme étendue d'inserts interchangeables, ce système peut être utilisé pour un large éventail d'applications avec les agitateurs magnétiques à plaque chauffante des gammes RCT, RET ou RH.

Image du produit-BSBTPB10003

Anti-INA Rabbit Polyclonal Antibody

Numéro de catalogue: (BSBTPB10003)
Fournisseur: Boster Bio
Description: Alpha-Internexin (INA; also NF-66) is a 66 kDa member of the intermediate filament (IF) protein family. The protein was originally purified from rat optic nerve and spinal cord. And the protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the Central Nervous System of adults. Meanwhile, the protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.
UOM: 1 * 1 EA
Image du produit-LENZ05015024

Adaptateurs à trois cols

Fournisseur: Lenz Laborglas GmbH & CO.KG
Description: DURAN® Borosilicate glass 3.3

Image non disponible-BOSSBS-1126R-CY7

Anti-5-HT Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-1126R-CY7)
Fournisseur: Bioss
Description: Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-0980R-A350

Anti-CD38 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-0980R-A350)
Fournisseur: Bioss
Description: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1126R-A488

Anti-5-HT Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-1126R-A488)
Fournisseur: Bioss
Description: Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-0980R-CY3

Anti-CD38 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-0980R-CY3)
Fournisseur: Bioss
Description: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-0980R-HRP

Anti-CD38 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-0980R-HRP)
Fournisseur: Bioss
Description: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1126R-HRP

Anti-5-HT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-1126R-HRP)
Fournisseur: Bioss
Description: Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
UOM: 1 * 100 µl
Image du produit-LENZ03304176

Fioles à fond rond avec trois cols et joints rodés standard

Fournisseur: Lenz Laborglas GmbH & CO.KG
Description: En verre borosilicaté DURAN®, avec deux cols latéraux parallèles, transparent.

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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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