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Image non disponible-BNCB1054-500

Anti-HLA-A; HLA-B; HLA-C Mouse Monoclonal Antibody (Biotin) [clone: 246-B8.E7]

Fournisseur: Biotium
Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Image du produit-HACH2587200

Kits de couleurs visuels, glutaraldéhyde

Numéro de catalogue: (HACH2587200)
Fournisseur: Hach
Description: Les kits de test pour glutaraldéhyde sont conçus pour surveiller les processus de désinfection.
UOM: 1 * 1 KIT
Image du produit-620-2334

VWR® Traceable® Ultra, Thermomètres à triple affichage

Fournisseur: VWR Collection
Description: Les thermomètres numériques sont conçus pour surveiller avec précision la température des réfrigérateurs, des congélateurs, des incubateurs, des bains-marie ou pendant le transport, dans une ou deux zones différentes avec des capteurs à température tampon fermés ou des capteurs à balle.

Image du produit-710-0738

NBB®-B-AM, bouillon

Numéro de catalogue: (710-0738)
Fournisseur: DOEHLER GROUP
Description: Milieu de culture pour la détection qualitative des microorganismes indicateurs à l'aide d'une méthode d'écouvillonnage réalisée avec des écouvillons stériles dans le cadre de la surveillance microbiologique de l'équipement. Sous sa marque NBB®, Döhler propose des milieux de culture innovants pour la détection rapide et fiable des microorganismes contaminant les boissons (par exemple, les bactéries Lactobacillus, Pectinatus et Megasphaera), et ce dans tous les échantillons provenant de brasseries, ainsi que pour l'industrie du vin. NBB®-B-AM est un milieu de culture liquide qui permet de détecter les microorganismes indicateurs de biofilms.
UOM: 1 * 9 ST

MSMD Certificats


Image non disponible-CAMA022.9850

CAMAG® TLC Visualizer 3 Documentation System

Numéro de catalogue: (CAMA022.9850)
Fournisseur: CAMAG
Description: <p>CAMAG® TLC Visualizer 3 documentation system with 12 mm lens, without visionCATS software. Suited for object formats up to about 21×28 cm (20×20 cm TLC plates).</p>
UOM: 1 * 1 ST

New Product


Image du produit-171-0872

Système de purification de l'eau, avec surveillance UV et COT, PURELAB® Flex 2

Numéro de catalogue: (171-0872)
Fournisseur: ELGA LabWater
Description: Le système PURELAB flex 2 allie simplicité d'utilisation et distribution précise d'eau pure. Le système modulaire flexible peut être configuré pour assurer la qualité d'eau dont vous avez besoin pour vos applications et comprend la surveillance de la photo-oxydation par UV et du carbone organique total (COT).
Distribue jusqu'à 2 litres par minute d'eau de type I.
UOM: 1 * 1 ST
Image non disponible-BOSSBS-7108R-A488

Anti-PARP3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-7108R-A488)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-BNC041095-100

Anti-HLA-A Mouse Monoclonal Antibody (CF405S) [clone: 108-2C5]

Fournisseur: Biotium
Description: HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of the α1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of the α1 domain was demonstrated in the formation of an intralocus HLA-A determinant.

Image du produit-BOSSBS-5221R

Anti-BRCA1 Rabbit Polyclonal Antibody

Numéro de catalogue: (BOSSBS-5221R)
Fournisseur: Bioss
Description: This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM: 1 * 100 µl
Image non disponible-BOSSBS-2566R-CY3

Anti-CLEC6A Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-2566R-CY3)
Fournisseur: Bioss
Description: Dectin 2 is a type II transmembrane protein that is a member of the C type lectin superfamily. In mouse, dectin 2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin 2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin 2 but transient up regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin 2 has not been fully determined but studies suggest a possible role in immune surveillance.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7108R-A350

Anti-PARP3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-7108R-A350)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-CY5

Anti-FANCM Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-13143R-CY5)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-HRP

Anti-FANCM Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-13143R-HRP)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-A647

Anti-FANCM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-13143R-A647)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13120R-A350

Anti-EXOSC10 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-13120R-A350)
Fournisseur: Bioss
Description: The exosome is a multi-subunit complex composed of several highly conserved proteins, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. EXOSC10, also known as PMSCL, PMSCL2, p2, p3, p4, RRP6, Rrp6p, PM-Scl, or PM/Scl-100, is an 885 amino acid protein that contains one HRDC domain and one 3’-5’ enonuclease domain. Localized to both the cytoplasm and the nucleus, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons. against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, respectively), suggesting that EXOSC10 may be involved in the pathogenesis of these diseases. Two isoforms of EXOSC10 exist due to alternative splicing events.
UOM: 1 * 100 µl
Image du produit-620-2426

VWR® Traceable®, Thermomètre numérique à enregistrement de données, réfrigérateur et congélateur

Numéro de catalogue: (620-2426)
Fournisseur: VWR Collection
Description: Thermomètre à enregistrement des données pouvant être utilisé dans des environnements 21 CFR 11. Parfaits pour surveiller les températures dans les réfrigérateurs, les congélateurs, les bains-marie, les blocs de chauffage et les incubateurs.
UOM: 1 * 1 ST
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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