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Image non disponible-BOSSBS-7108R-A555

Anti-PARP3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-7108R-A555)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7108R-HRP

Anti-PARP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-7108R-HRP)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-CHRASM302

Serratia Base

Numéro de catalogue: (CHRASM302)
Fournisseur: CHROMAGAR
Description: Serratia species are implicated in nosocomial infections. In several countries, <i>Serratia marcescens</i> is frequently associated with epidemics in intensive care units and in particular in neonatal and pediatric units. Surveillance of nosocomial infections requires effective recovery of clinical isolates from faeces, wound exudates and respiratory samples to prevent problems of cross infection and potentially fatal infections. In this context, CHROMagar™ has developed CHROMagar™ Serratia, a culture medium perfectly suited to the search for <i>S. marcescens</i> in faeces. In addition, <i>S. marcescens</i> is able to survive days to months on surfaces, distilled water and hand soap, making it an important pathogen in nosocomial infections and sporadic epidemics.
UOM: 1 * 1 ST
Image du produit-620-2334

VWR® Traceable® Ultra, Thermomètres à triple affichage

Fournisseur: VWR Collection
Description: Les thermomètres numériques sont conçus pour surveiller avec précision la température des réfrigérateurs, des congélateurs, des incubateurs, des bains-marie ou pendant le transport, dans une ou deux zones différentes avec des capteurs à température tampon fermés ou des capteurs à balle.

Image non disponible-BOSSBS-15430R-A555

Anti-HCST Rabbit Polyclonal Antibody (ALEXA FLUOR® 555)

Numéro de catalogue: (BOSSBS-15430R-A555)
Fournisseur: Bioss
Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
UOM: 1 * 100 µl
Image du produit-620-2302

VWR® Traceable®, Thermomètres numériques pour réfrigérateurs

Numéro de catalogue: (620-2302)
Fournisseur: VWR Collection
Description: Ce thermomètre est conçu pour surveiller les températures dans les entrepôts, laboratoires, bureaux et hottes d’aspiration. Il est livré avec des dispositifs de fixation pour un positionnement souple.
UOM: 1 * 1 ST
Image non disponible-BOSSBS-7108R-CY3

Anti-PARP3 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-7108R-CY3)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-BNCB1054-100

Anti-HLA-A; HLA-B; HLA-C Mouse Monoclonal Antibody (Biotin) [clone: 246-B8.E7]

Fournisseur: Biotium
Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Image du produit-HUBE3004.0004.99

Refroidisseurs à immersion, gamme TC

Fournisseur: HUBER
Description: La gamme de refroidisseurs à immersion TC représente une solution flexible pour une variété de tâches de refroidissement directe de liquides. Applications types : refroidissement des thermostats à circulation ou remplacement du système de refroidissement par de la glace sèche. Les refroidisseurs à immersion TC peuvent être utilisés sans surveillance, pour des tâches nécessitant un refroidissement continu ou comme solution alternative avec contrôle de la température et sonde PT100. Les refroidisseurs à immersion TC peuvent être utilisés sans surveillance, pour des tâches nécessitant un refroidissement continu.

Image du produit-HACH2587200

Kits de couleurs visuels, glutaraldéhyde

Numéro de catalogue: (HACH2587200)
Fournisseur: Hach
Description: Les kits de test pour glutaraldéhyde sont conçus pour surveiller les processus de désinfection.
UOM: 1 * 1 KIT
Image non disponible-BOSSBS-7108R-FITC

Anti-PARP3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-7108R-FITC)
Fournisseur: Bioss
Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-CY5

Anti-FANCM Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-13143R-CY5)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-HRP

Anti-FANCM Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-13143R-HRP)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-A647

Anti-FANCM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-13143R-A647)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13120R-A350

Anti-EXOSC10 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-13120R-A350)
Fournisseur: Bioss
Description: The exosome is a multi-subunit complex composed of several highly conserved proteins, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. EXOSC10, also known as PMSCL, PMSCL2, p2, p3, p4, RRP6, Rrp6p, PM-Scl, or PM/Scl-100, is an 885 amino acid protein that contains one HRDC domain and one 3’-5’ enonuclease domain. Localized to both the cytoplasm and the nucleus, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons. against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, respectively), suggesting that EXOSC10 may be involved in the pathogenesis of these diseases. Two isoforms of EXOSC10 exist due to alternative splicing events.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13143R-CY7

Anti-FANCM Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-13143R-CY7)
Fournisseur: Bioss
Description: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.
UOM: 1 * 100 µl
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