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Image non disponible-BOSSBS-10994R-A750

Anti-DNA PKcs Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-10994R-A750)
Fournisseur: Bioss
Description: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localisation of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-10994R-A647

Anti-PRKDC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-10994R-A647)
Fournisseur: Bioss
Description: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM: 1 * 100 µl
Image du produit-216-5524

Accessoires pour bonbonnes, avec vis Bouchon

Fournisseur: Kautex
Description: Accessoires pour bonbonnes, avec vis Bouchon

Image du produit-118-0320

Gas detection tube for hydrogen sulphide

Fournisseur: Dräger
Description: To measure the 'spot concentrations' of hydrogen sulphide for use with an Accuro® pump. Uses include determination and measurement of concentration peaks, measurement of personal exposure in the inhalation area, detection of leaks in, for example, pipelines or gas installations, and air analysis in sewers, shafts and confined spaces.

Image du produit-151-3148

Gas detection tubes for phosgene

Numéro de catalogue: (151-3148)
Fournisseur: Dräger
Description: To measure the 'spot concentrations' of phosgene for use with an accuro® pump - Uses include determination and measurement of concentration peaks, personal exposure in the inhalation area, detection of leaks in pipelines or gas installations, and air analysis in sewers, shafts and confined spaces.
UOM: 1 * 10 ST
Image du produit-BIND8012-2160

Accessories for drying ovens with natural convection, ED Series

Fournisseur: Binder
Description: Accessories for drying ovens with natural convection, ED Series

Image non disponible-MILFPHCC3BEADS

Accessories for Scepter™ 3.0 Automated Cell Counter Kits

Fournisseur: Merck
Description: Accessories for Scepter™ 3.0 Automated Cell Counter Kits

New Product

Image du produit-MEMMB04358UN75PA

Trays for Memmert UNpa ovens

Fournisseur: MEMMERT
Description: Trays for Memmert UNpa ovens

Image non disponible-ABCAAB308386-100

Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: HL1464]

Numéro de catalogue: (ABCAAB308386-100)
Fournisseur: Abcam
Description: Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: HL1464]
UOM: 1 * 100 µl
Image du produit-151-0164

Gas detection tube for xylene

Numéro de catalogue: (151-0164)
Fournisseur: Dräger
Description: To measure the 'spot concentrations' of xylene for use with an Accuro® pump. Cross sensitivity<B>: </B>Styrene, vinyl acetate, toluene, ethyl benzene and acetaldehyde are indicated, but with different sensitivities. No interference by:
UOM: 1 * 10 ST
Image non disponible-BOSSBS-10994R-A488

Anti-PRKDC Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-10994R-A488)
Fournisseur: Bioss
Description: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM: 1 * 100 µl
Image du produit-151-0192

Gas detection tubes for acetone

Fournisseur: Dräger
Description: To measure the 'spot concentrations' of acetone for use with an Accuro pump. Uses include determination and measurement of concentration peaks, personal exposure in the inhalation area, detection of leaks in pipelines or gas installations, air analysis in sewers, shafts and confined spaces.

Image du produit-151-0152

Gas detection tubes for hydrochloric acid

Numéro de catalogue: (151-0152)
Fournisseur: Dräger
Description: To measure the 'spot concentrations' of hydrochloric acid in the air with an Accuro® pump - Uses include determination and measurement of concentration peaks, personal exposure in the inhalation area, detection of leaks in pipelines or gas installations, air analysis in sewers, shafts and confined spaces.
UOM: 1 * 10 ST
Image non disponible-ABCAAB308418-100

Anti-Strep Tag Rabbit Monoclonal Antibody [clone: HL1251]

Numéro de catalogue: (ABCAAB308418-100)
Fournisseur: Abcam
Description: Anti-Strep Tag Rabbit Monoclonal Antibody [clone: HL1251]
UOM: 1 * 100 µl
Image non disponible-STUA04807-56

Cole-Parmer® ST-200 Series Undergrad Analogue Magnetic Stirrer

Numéro de catalogue: (STUA04807-56)
Fournisseur: Cole Parmer
Description: Powerful and precision stirring in compact size.
UOM: 1 * 1 ST
Image du produit-479-4154

Tubes Cryo.S™ 4 et 5 ml

Fournisseur: Greiner Bio-One
Description: Pour le stockage en congélateur ou dans la phase vapeur d'azote liquide. Résistance thermique de -196 à +121 °C.

Environmentally Preferable

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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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