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Image non disponible-BOSSBS-1288G-CY5.5

Anti-GDF8 Goat Polyclonal Antibody (Cy5.5®)

Description: Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
Numéro de catalogue: BOSSBS-1288G-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-3449R-CY7

Anti-TEK Rabbit Polyclonal Antibody (Cy7®)

Description: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
Numéro de catalogue: BOSSBS-3449R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-3449R-A680

Anti-Tie2 Tyr992 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
Numéro de catalogue: BOSSBS-3449R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1350R-A750

Anti-DAP-5/p97 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
Numéro de catalogue: BOSSBS-1350R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1350R-CY3

Anti-EIF4G2 Rabbit Polyclonal Antibody (Cy3®)

Description: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
Numéro de catalogue: BOSSBS-1350R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BNC880922-100

Anti-PDCD1 Mouse Monoclonal Antibody (CF488A) [clone: PDCD1/922]

Description: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Numéro de catalogue: BNC880922-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image non disponible-BOSSBS-4726R-A680

Anti-GCDFP15 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterised by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
Numéro de catalogue: BOSSBS-4726R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-5751R-CY5.5

Anti-MATK Rabbit Polyclonal Antibody (Cy5.5®)

Description: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Numéro de catalogue: BOSSBS-5751R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-5751R-A750

Anti-MATK Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Numéro de catalogue: BOSSBS-5751R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-12477R-A647

Anti-ANXA11 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
Numéro de catalogue: BOSSBS-12477R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-4307R-CY3

Anti-DEFB4A Rabbit Polyclonal Antibody (Cy3®)

Description: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways
Numéro de catalogue: BOSSBS-4307R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-ENZOALX350168C025

[D-Asp3]microcystin-RR

Description: Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.
Numéro de catalogue: ENZOALX350168C025
UOM: 1 * 25 µG
Fournisseur: ENZO LIFE SCIENCES
Image non disponible-BOSSBS-5751R-HRP

Anti-MATK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Numéro de catalogue: BOSSBS-5751R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-12580R-FITC

Anti-ARID3B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Numéro de catalogue: BOSSBS-12580R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1471R-A647

Anti-Annexin VI Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The Annexin family of calcium binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.
Numéro de catalogue: BOSSBS-1471R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-0953R-CY5.5

Anti-CGB5 Rabbit Polyclonal Antibody (Cy5.5®)

Description: This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq].
Numéro de catalogue: BOSSBS-0953R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
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