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Numéro de catalogue: (BOSSBS-5040R-A350)

Fournisseur: Bioss

Description: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

UOM: 1 * 100 µl

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Numéro de catalogue: (BOSSBS-5040R-A680)

Fournisseur: Bioss

Description: Involved in bile acid metabolism. In liver hepatocytes catalyses the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyse the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyses the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

UOM: 1 * 100 µl

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Fournisseur: Molekula

Description: Acide N-(acétamido-2)-amino-2-éthanesulfonique (ACES)

Numéro de catalogue: (PRSI26-066)

Fournisseur: ProSci Inc.

Description: BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.

UOM: 1 * 50 µG

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Numéro de catalogue: (A1060.1000)

Fournisseur: PanReac AppliChem

Description: Acide N-(acétamido-2)-amino-2-éthanesulfonique (ACES)

UOM: 1 * 1 kg

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Fournisseur: Thermo Fisher Scientific

Description: Acide N-(acétamido-2)-amino-2-éthanesulfonique (ACES) 99+% pour biochimie

MSMD

Fournisseur: MP Biomedicals

Description: Glyceryl Monooleate is a surfactant that releases free glycerol and oleic acid upon hydrolysis.

Fournisseur: MP Biomedicals

Description: Applications
Taurocholic Acid Sodium Salt is an anionic detergent used for protein solubilization.
Product Description
Taurocholic Acid Sodium Salt is the conjugation product of cholic acid with taurine and the principal constituent of the bile of carnivorous animals.
Biochem/physiol Actions
Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Melting Point: 230 °C (decomposes)(Lit.)
Presentation: White Powder
Format: Powder
pH: 6 - 7.5(1% aq soln)
Aggregation Number: 4
Critical Micelle Concentration (CMC): 3-11 mM
Heavy Metals: =20 ppm
Loss on Drying: =7.0%
NOTES: Sodium Cholate : =3.0%
Solubility: Soluble in water (100 mg/mL).
Storage & Handling: Store at Room Temperature (15-30 °C).

Fournisseur: MP Biomedicals

Description: Cholic acid is a biochemical solubilizing agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.

Certificats

Numéro de catalogue: (8.08616.9025)

Fournisseur: Merck

Description: TAURINE POUR LA SYNTHESE 1 * 25 kg

UOM: 1 * 25 kg

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Numéro de catalogue: (ABCAAB141063-1)

Fournisseur: Abcam

Description: TAURINE 1 * 1 g

UOM: 1 * 1 g

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Numéro de catalogue: (CAYM9000629-10)

Fournisseur: Cayman Chemical

Description: OLEOYL SEROTONIN 1 * 10 mg

UOM: 1 * 10 mg

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Numéro de catalogue: (CAYM10011357-10)

Fournisseur: Cayman Chemical

Description: GLYCEROPHOSPHO-N-OLEOYL ETHANOLAMINE 1 * 10 mg

UOM: 1 * 10 mg

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Numéro de catalogue: (CAYM62215-1)

Fournisseur: Cayman Chemical

Description: 1-OLEOYL LYSOPHOSPHATIDIC ACID (SODIUM 1 * 1 mg

UOM: 1 * 1 mg

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Numéro de catalogue: (CAYM62600-5)

Fournisseur: Cayman Chemical

Description: 1-OLEOYL-2-ACETYL-SN-GLYCEROL 1 * 5 mg

UOM: 1 * 5 mg

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Numéro de catalogue: (CAYM20959-1)

Fournisseur: Cayman Chemical

Description: 1-Oleoyl-2-hydroxy-sn-glycero-3-PC 1 * 1 mg

UOM: 1 * 1 mg

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