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Malonyl coenzyme A lithium salt ≥90%

Fournisseur: Cayman Chemical
Description: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image non disponible-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Fournisseur: Merck
Description: Organic Standard, Malonyl-ʟ-carnitine lithium salt

Image non disponible-CAYM10005647-50

Cerulenin ≥98%, solide cristallin

Fournisseur: Cayman Chemical
Description: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image non disponible-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-12952R-A680)
Fournisseur: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-12954R-A680)
Fournisseur: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Numéro de catalogue: (BOSSBS-12954R-A750)
Fournisseur: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-12952R-A750)
Fournisseur: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image non disponible-APOSBIC7401-100MG

Coenzyme A trilithium salt

Fournisseur: Apollo Scientific
Description: Coenzyme A trilithium salt

Image non disponible-CAYM10547-5

4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, poudre lyophilisée

Fournisseur: Cayman Chemical
Description: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, poudre lyophilisée

Image non disponible-CAYM21722-10

Coenzyme A sodium salt hydrate ≥95%

Fournisseur: Cayman Chemical
Description: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

Image non disponible-8.22084.0250

L(+)-Lactate de lithium pour la synthèse, Sigma-Aldrich®

Fournisseur: Merck
Description: L(+)-Lactate de lithium pour la synthèse, Sigma-Aldrich®

MSMD

Image non disponible-73885-10MG

Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Fournisseur: Merck
Description: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt

Image non disponible-89921-10MG

Supelco® Organic Reference Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Fournisseur: Merck
Description: Organic Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Image non disponible-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Numéro de catalogue: (55385-10MG)
Fournisseur: Merck
Description: Organic Standard, 3-Phosphoshikimic acid lithium salt
UOM: 1 * 10 mg
Image du produit-0782-100G

Lithium dodécyle sulfate 99, high_purity

Fournisseur: VWR Chemicals
Description: Lithium dodécyle sulfate 99, high_purity

MSMD

Image du produit-85793.150

Lithium dodécyle sulfate ≥98.5%, HiPerSolv CHROMANORM® pour HPLC

Numéro de catalogue: (85793.150)
Fournisseur: VWR Chemicals
Description: Lithium dodécyle sulfate ≥98.5%, HiPerSolv CHROMANORM® pour HPLC
UOM: 1 * 25 g

MSMD Certificats


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