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Image non disponible-BOSSBS-1520R-CY7

Anti-CD7 Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-1520R-CY7)
Fournisseur: Bioss
Description: CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-12477R-FITC

Anti-ANXA11 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-12477R-FITC)
Fournisseur: Bioss
Description: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1799R-A647

Anti-GRIA3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-1799R-A647)
Fournisseur: Bioss
Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-A555

Anti-FZD9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-11842R-A555)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-A647

Anti-FZD9 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-11842R-A647)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13239R-FITC

Anti-FZD3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-13239R-FITC)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5125R-CY3

Anti-FZD7 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-5125R-CY3)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-A488

Anti-FZD9 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-11842R-A488)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-A350

Anti-FZD9 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-11842R-A350)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3401R-CY3

Anti-PTK2B Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-3401R-CY3)
Fournisseur: Bioss
Description: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3995R-HRP

Anti-SLC16A7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-3995R-HRP)
Fournisseur: Bioss
Description: Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]).[supplied by OMIM, Feb 2011].
UOM: 1 * 100 µl
Image non disponible-BOSSBS-0520R-A555

Anti-PRKCA + PRKCB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-0520R-A555)
Fournisseur: Bioss
Description: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13391R-CY5

Anti-GRIA1 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-13391R-CY5)
Fournisseur: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-10042R-FITC

Anti-GRIA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-10042R-FITC)
Fournisseur: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-10042R-CY7

Anti-GRIA1 Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-10042R-CY7)
Fournisseur: Bioss
Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9044R-CY3

Anti-TRPM7 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-9044R-CY3)
Fournisseur: Bioss
Description: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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