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Image non disponible-BOSSBS-1799R-CY3

Anti-GRIA3 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-1799R-CY3)
Fournisseur: Bioss
Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6709R-CY5

Anti-PLA2G6 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-6709R-CY5)
Fournisseur: Bioss
Description: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11754R-A680

Anti-SCGN/Secretagogin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-11754R-A680)
Fournisseur: Bioss
Description: SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13216R-A750

Anti-Frizzled 10/CD350 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-13216R-A750)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3961R-CY3

Anti-NDUFS4 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-3961R-CY3)
Fournisseur: Bioss
Description: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1799R-A488

Anti-GRIA3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-1799R-A488)
Fournisseur: Bioss
Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6709R-A350

Anti-PLA2G6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-6709R-A350)
Fournisseur: Bioss
Description: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-6709R-A488

Anti-PLA2G6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-6709R-A488)
Fournisseur: Bioss
Description: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-A750

Anti-Frizzled 9/CD349 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-11842R-A750)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical Signalling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second Signalling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11842R-CY5

Anti-FZD9 Rabbit Polyclonal Antibody (Cy5®)

Numéro de catalogue: (BOSSBS-11842R-CY5)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13239R-A555

Anti-FZD3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-13239R-A555)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13216R-A488

Anti-FZD10 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-13216R-A488)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13216R-CY3

Anti-FZD10 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-13216R-CY3)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13216R-FITC

Anti-FZD10 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-13216R-FITC)
Fournisseur: Bioss
Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-0520R-FITC

Anti-PRKCA + PRKCB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-0520R-FITC)
Fournisseur: Bioss
Description: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1471R-A555

Anti-Annexin VI Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-1471R-A555)
Fournisseur: Bioss
Description: The Annexin family of calcium binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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