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Image du produit-PRSI6755

Anti-TSHZ1 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI6755)
Fournisseur: ProSci Inc.
Description: TSHZ1 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.
UOM: 1 * 1 EA
Image du produit-PRSI6759

Anti-TSHZ3 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI6759)
Fournisseur: ProSci Inc.
Description: TSHZ3 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.
UOM: 1 * 1 EA
Image du produit-PRSI4485

Anti-SIRT2 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI4485)
Fournisseur: ProSci Inc.
Description: SIRT2 Antibody: The founding member of the sirtuin protein family was the silent information regulator 2 protein (Sir2p) of Saccharomyces cervisiae, an NAD+-dependent histone deacetylase (HDAC) that regulates chromatin silencing. The SIR2 family of genes are highly conserved from prokaryotes to eukaryotes. Mammals have seven homologs of Sir2p, SIRT1-7, which are involved in diverse processes ranging from transcriptional regulation, cell cycle progression and DNA-damage repair to aging. SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules and can deacetylate alpha-tubulin and regulate progression through the cell cycle. Most Sirtuins are highly expressed in brain and testis, while Sirt2 expression is higher in fetal relative to adult brain. Recent studies on SIRT2 support the therapeutic utility of inhibitors for the treatment of neurodegenerative diseases such as Parkinson's disease.
UOM: 1 * 1 EA
Image non disponible-ENZOENZCHM1250005

Akt inhibitor VIII ≥98% (par HPLC)

Fournisseur: ENZO LIFE SCIENCES
Description: Potent inhibitor of Akt1, Akt2 and Akt3 activity.

Image non disponible-TCIAA3153-100MG

Akt inhibitor VIII ≥97.0% (par HPLC)

Numéro de catalogue: (TCIAA3153-100MG)
Fournisseur: TCI
Description: Akt inhibitor VIII ≥97.0% (par HPLC)
UOM: 1 * 100 mg
Image non disponible-ENZOBMLKI1780005

Fluor-de-Lys® HDAC8 deacetylase Substrate

Numéro de catalogue: (ENZOBMLKI1780005)
Fournisseur: ENZO LIFE SCIENCES
Description: Fluor de Lys®-HDAC8 is a fluorogenic, diacetylated peptide substrate for HDAC8 (histone deacetylase-8).
UOM: 1 * 1 VIA
Image non disponible-BOSSBS-3127R-A488

Anti-HDAC8 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numéro de catalogue: (BOSSBS-3127R-A488)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3127R-A680

Anti-HDAC8 Ser39 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-3127R-A680)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3127R-CY3

Anti-HDAC8 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-3127R-CY3)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3127R-A350

Anti-HDAC8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-3127R-A350)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3127R-A647

Anti-HDAC8 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-3127R-A647)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3127R-CY7

Anti-HDAC8 Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-3127R-CY7)
Fournisseur: Bioss
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5387R-FITC

Anti-HDAC1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-5387R-FITC)
Fournisseur: Bioss
Description: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5387R-CY7

Anti-HDAC1 Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-5387R-CY7)
Fournisseur: Bioss
Description: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7134R-A680

Anti-SPOP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-7134R-A680)
Fournisseur: Bioss
Description: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5387R-A350

Anti-HDAC1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-5387R-A350)
Fournisseur: Bioss
Description: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family.
UOM: 1 * 100 µl
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