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Numéro de catalogue: (BOSSBS-0076R-CY5.5)
Fournisseur: Bioss
Description: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
UOM: 1 * 100 µl


Fournisseur: THERMO MATRIX TECHNOLOGIES
Description: Pour la prévention de la contamination et des éclaboussures d'échantillons.

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Numéro de catalogue: (BOSSBS-11063R)
Fournisseur: Bioss
Description: Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains, and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin-1 mediates increases in desmosomal protein content, desmosome assembly, and regulation of cell migration. Plakophilin-2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin-3 plays a role in both desmosome-dependent adhesion and signaling pathways. Plakophilin-4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-11643R-A555)
Fournisseur: Bioss
Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-11643R-CY7)
Fournisseur: Bioss
Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-11643R-FITC)
Fournisseur: Bioss
Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-11643R-CY5)
Fournisseur: Bioss
Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-6585R-FITC)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-6585R-A680)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-6585R-A350)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-10152R-A350)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-10152R-A750)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-10152R-FITC)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-10152R-A680)
Fournisseur: Bioss
Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
UOM: 1 * 100 µl


Numéro de catalogue: (ENZOALX804656R100)
Fournisseur: ENZO LIFE SCIENCES
Description: α-synuclein, an acidic neuronal protein of 140 aa, has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and to be an important regulatory component of vesicular transport in neuronal cells. The NAC (non-Aβ component of amyloid plaques) domain (aa 61-95) of α-synuclein is an highly amyloidogenic peptide which was first identified associated with senile plaques in the Alzheimer's disease brain.
UOM: 1 * 100 µl


Numéro de catalogue: (BOSSBS-6815R-A350)
Fournisseur: Bioss
Description: LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.
UOM: 1 * 100 µl


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