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Image non disponible-BNC880861-100

Anti-HSPB1 Mouse Monoclonal Antibody (CF488A) [clone: G3.1]

Description: This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian α-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.
Numéro de catalogue: BNC880861-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image non disponible-BOSSBS-15541R-CY7

Anti-IDN3 Rabbit Polyclonal Antibody (Cy7)

Description: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterised by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Numéro de catalogue: BOSSBS-15541R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-15541R-CY5

Anti-IDN3 Rabbit Polyclonal Antibody (Cy5)

Description: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterised by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Numéro de catalogue: BOSSBS-15541R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-8320R-A680

Anti-HEATR3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: HEATR3 is a 680 amino acid protein existing as three alternatively spliced isoforms and containing two HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR3 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterised by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.
Numéro de catalogue: BOSSBS-8320R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BNUB0861-100

Anti-HSPB1 Mouse Monoclonal Antibody (Purified) [clone: G3.1]

Description: This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian α-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.
Numéro de catalogue: BNUB0861-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image non disponible-BNC940851-100

Anti-HSPD1 Mouse Monoclonal Antibody (CF594) [clone: LK1]

Description: Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp), more appropriately called as stress response proteins (srp). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.
Numéro de catalogue: BNC940851-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image du produit-733-2877

Solution d'extraction rapide d'ADN, VWR®

Description: La solution d'extraction rapide d'ADN permet une extraction prompte et efficace d'ADN prêt pour la PCR à partir de tissus de mammifères. L'ADN est prêt en huit minutes. Le protocole à un seul réactif est divisé en deux étapes simples de chauffage, qui peuvent être directement suivies d'une analyse PCR, comme le dépistage et le génotypage.
Numéro de catalogue: 733-2877
UOM: 1 * 500 Tests
Fournisseur: VWR Chemicals
Image non disponible-BOSSBS-1926R-CY5

Anti-UCP2 Rabbit Polyclonal Antibody (Cy5®)

Description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).
Numéro de catalogue: BOSSBS-1926R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-1926R-CY7

Anti-UCP2 Rabbit Polyclonal Antibody (Cy7®)

Description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).
Numéro de catalogue: BOSSBS-1926R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-8320R-HRP

Anti-HEATR3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: HEATR3 is a 680 amino acid protein existing as three alternatively spliced isoforms and containing two HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR3 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.
Numéro de catalogue: BOSSBS-8320R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image non disponible-BOSSBS-8320R-CY3

Anti-HEATR3 Rabbit Polyclonal Antibody (Cy3®)

Description: HEATR3 is a 680 amino acid protein existing as three alternatively spliced isoforms and containing two HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR3 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.
Numéro de catalogue: BOSSBS-8320R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image du produit-WHEA225277

Headspace vials, WHEATON®

Description: These vials made of type I borosilicate glass feature rounded shoulders and bottoms, allowing for even heating and safer operation at higher pressures.
Numéro de catalogue: WHEA225277
UOM: 1 * 100 ST
Fournisseur: DWK Life Sciences
Image non disponible-BOSSBS-11623R-A750

Anti-PIRT Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, while VR1 remains unaltered. The gene that encodes PIRT maps to human chromosome 17p13.1.
Numéro de catalogue: BOSSBS-11623R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Image du produit-462-0559

VWR® VWB2, Bains-marie

Description: Bains-marie non agités avec boîtier en acier inoxydable (intérieur) à double paroi et en tôle d’acier revêtue (extérieur). Tous les bains, à l’exception des modèles de 2 litres, disposent d’un robinet de drainage pour une vidange facile et peuvent être utilisés avec de l’eau ou avec des billes de transfert de chaleur. Les bains d’une capacité de 5 litres ou plus ont un mode à billes de transfert de chaleur qui est activé via le menu principal. Un bouchon de vidange est fourni comme accessoire optionnel afin d’éviter que les billes de transfert de chaleur ne restent coincées dans la sortie de drainage. Remarque : les bains-marie appartiennent à la classe de sécurité 1, ce qui leur permet de fonctionner sans surveillance avec des liquides non inflammables.
Numéro de catalogue: 462-0559
UOM: 1 * 1 ST
Fournisseur: VWR Collection
Image du produit-129-2650

Sachets autoclave avec indicateur de vapeur, thermosoudure, Tyvek® 1073B

Description: Les sacs Tyvek® 1073B sont idéaux pour la stérilisation à la vapeur de composants pharmaceutiques tels que les bouchons et les capuchons de flacons et de seringues, ainsi que les pièces d'équipement lourdes aux bords tranchants.
Numéro de catalogue: 129-2650
UOM: 1 * 50 ST
Fournisseur: KEYSTONE CLEANROOM PRODUCTS
Image du produit-KOTT451-00000

Pharmacy fume hoods, benchtop

Description: The pharmacy hood is a small hood, which was developed especially for the handling of hazardous substances in pharmacies. It complies with the requirements of section 4 (2) of the German Pharmacies Act and is ideally suited for handling dusty compounds or volatile chemicals. These hoods have been designed for safe handling of chemicals, mineral acids, concentrated and heated acids.
Numéro de catalogue: KOTT451-00000
UOM: 1 * 1 ST
Fournisseur: KOETTERMANN
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