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Image non disponible-BOSSBS-13228R-CY3

Anti-FURIN Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-13228R-CY3)
Fournisseur: Bioss
Description: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1077R-A750

Anti-2-Oct Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-1077R-A750)
Fournisseur: Bioss
Description: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1077R-A680

Anti-2-Oct Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-1077R-A680)
Fournisseur: Bioss
Description: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image du produit-BOSSBS-11994R

Anti-Phosphoserine/threonine Rabbit Polyclonal Antibody

Numéro de catalogue: (BOSSBS-11994R)
Fournisseur: Bioss
Description: A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The (Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7042R-A680

Anti-ELF1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numéro de catalogue: (BOSSBS-7042R-A680)
Fournisseur: Bioss
Description: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-7042R-A647

Anti-ELF1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numéro de catalogue: (BOSSBS-7042R-A647)
Fournisseur: Bioss
Description: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13228R-A555

Anti-FURIN Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numéro de catalogue: (BOSSBS-13228R-A555)
Fournisseur: Bioss
Description: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-13228R-A350

Anti-FURIN Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numéro de catalogue: (BOSSBS-13228R-A350)
Fournisseur: Bioss
Description: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11805R-FITC

Anti-ZFHX3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numéro de catalogue: (BOSSBS-11805R-FITC)
Fournisseur: Bioss
Description: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1077R-CY5.5

Anti-POU2F2 Rabbit Polyclonal Antibody (Cy5.5®)

Numéro de catalogue: (BOSSBS-1077R-CY5.5)
Fournisseur: Bioss
Description: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5487R-A750

Anti-MAPK8 Thr183 + Tyr185 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numéro de catalogue: (BOSSBS-5487R-A750)
Fournisseur: Bioss
Description: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-1077R-CY3

Anti-POU2F2 Rabbit Polyclonal Antibody (Cy3®)

Numéro de catalogue: (BOSSBS-1077R-CY3)
Fournisseur: Bioss
Description: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-11805R-HRP

Anti-ZFHX3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numéro de catalogue: (BOSSBS-11805R-HRP)
Fournisseur: Bioss
Description: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
UOM: 1 * 100 µl
Image non disponible-BOSSBS-5590R-CY5.5

Anti-YWHAE Rabbit Polyclonal Antibody (Cy5.5®)

Numéro de catalogue: (BOSSBS-5590R-CY5.5)
Fournisseur: Bioss
Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-9253R

Anti-RNF133 Rabbit Polyclonal Antibody

Numéro de catalogue: (BOSSBS-9253R)
Fournisseur: Bioss
Description: RNF133 contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. RNF133 may have E3 ubiquitin-protein ligase activity.
UOM: 1 * 100 µl
Image non disponible-BOSSBS-3210R-CY7

Anti-JUN Rabbit Polyclonal Antibody (Cy7®)

Numéro de catalogue: (BOSSBS-3210R-CY7)
Fournisseur: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
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