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Image du produit-BIGNBC1506-4

Hottes à flux laminaire sans raccordement, Chemcap™ Clearview™

Numéro de catalogue: (BIGNBC1506-4)
Fournisseur: BIGNEAT
Description: Les hottes à flux laminaire sans raccordement Chemcap™ Clearview™ sont dotées d'un système de filtration au charbon Chemcap™. Gamme de six tailles de hotte standard avec un panneau de commande à clavier avec boutons tactiles et indicateur de maintenance. Comprend une lampe fluorescente 18 W et un plateau en PVC qui offre une excellente résistance chimique et retient les déversements.
Les hottes sont fabriquées en acier recouvert de polyester ; les panneaux transparents sont en acrylique et sont résistants à la corrosion.
UOM: 1 * 1 ST
Image du produit-HAKATSSWB15

Shaking water baths, Precision™

Fournisseur: THERMO ELECTRON LED
Description: Precision™ water baths support a range of sensitive life science and QA/QC applications, from warming fragile reagents to tissue culturing and genetics sequencing.

Image du produit-PRSI5267

Anti-CIP75 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI5267)
Fournisseur: ProSci Inc.
Description: CIP75 Antibody: The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal UBA domain which appears to mediate its interaction with Connexin-75. At least three isoforms of CIP75 are known to exist.
UOM: 1 * 1 EA
Image non disponible-HAKA1553211

Baths and circulators, stainless steel, SAHARA PPO S21P series

Fournisseur: THERMO ELECTRON LED
Description: These heated bath circulators maintains the ambient temperature. The SAHARA series of heated bath circulators are available with a wide variety of work area dimensions to meet internal or external circulation requirements.

Image du produit-PRSI79-244

Anti-HDAC4/5/9 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI79-244)
Fournisseur: ProSci Inc.
Description: Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general, they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the class to which they belong (class 1 HDACs are predominantly nuclear whilst class 2 HDACs shuttle between the nucleus and cytosol). HDACs have a role in cell growth arrest, differentiation and death and this has led to substantial interest in HDAC inhibitors as possible antineoplastic agents.
UOM: 1 * 1 EA
Image du produit-PRSI4271

Anti-IL33 Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI4271)
Fournisseur: ProSci Inc.
Description: IL-33 Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1 alpha /beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-kappa B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.
UOM: 1 * 1 EA
Image du produit-461-1241

Thermostat à immersion, Alpha

Numéro de catalogue: (461-1241)
Fournisseur: LAUDA
Description: Le thermostat à immersion Alpha est muni d'une console de commande simple avec trois boutons et un grand écran LED pour une navigation aisée dans les menus. Les thermostats conviennent à une utilisation dans les liquides non inflammables (eau, mélanges eau/glycol). Thermostatisation interne et externe. Stabilité thermique de ±0,05 K garantissant un chauffage précis. Convient pour de nombreuses applications. A l'aide d'un kit de pompe de circulation en option et du serpentin de refroidissement, le thermostat à immersion peut être transformé en système de thermostatisation complet.
UOM: 1 * 1 ST
Image du produit-HAKATSCIR19

Precision™ Circulating Water Baths

Fournisseur: THERMO ELECTRON LED
Description: <p>Ensure temperature uniformity and control with these Precision™ circulating water baths, which is particularly critical when working with enzymes and in serological applications. Available in three different models, these high performance baths feature a microprocessor control and include a removable stainless steel gable cover, diffuser tray, and rubber duck.</p>

Image du produit-HAKA1520011

Immersion thermostats

Fournisseur: THERMO ELECTRON LED
Description: Designed for ease-of-use and to be energy efficient with powerful pumping and heating capacities for closed loop applications.

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Image du produit-HAKA1551451

Baths and circulators, stainless steel, SAHARA series

Fournisseur: THERMO ELECTRON LED
Description: The SAHARA series are suitable for internal or external circulation and have a choice of eight different controllers that are suitable for various different applications.

Image du produit-EUTEECPHWP60001

pH/mV/°C meters, handheld, Eutech CyberScan pH 600 / 610 / 620

Fournisseur: EUTECH
Description: The CyberScan pH 600 series enables a wireless and cable-free data transfer with infrared IrDA technology. Data can be simply sent from the meter to a PC with the press of a button.

Image du produit-EUTEECPCWP65043K

Multi-parameter meter, handheld, Eutech CyberScan PC 650

Numéro de catalogue: (EUTEECPCWP65043K)
Fournisseur: EUTECH
Description: This portable meter enables users to measure pH, mV, conductivity, TDS, salinity, ions and temperature values. It simultaneously measures and displays up to three parameters.
UOM: 1 * 1 ST
Image du produit-441-0409

Heating circulators, HBC series

Fournisseur: IKA
Description: The HBC circulating baths have a high-quality stainless steel bath, an extended temperature range for tempering fluids in open and covered water baths up to 200/250 °C. The LED/ graphic TFT Display illustrates all relevant process parameters. The large surface of the radiator allows for an optimum heat exchange and a smooth warming of the medium. Units feature push and turn buttons for intuitive menu navigation. All models conform to the highest safety classification III (FL) for use with flammable liquids according to DIN 12876. HBC immersion circulators ensure short heating up times and have a temperature stability of ±0,01 /0,02 K ( basic/control model). The units have an integrated cooling coil, adjustable safety circuit and a front drain valve for safe emptying. To drain the system, a separate valve helps to avoid direct contact with fluid.

Image du produit-PRSI5437

Anti-GAS Rabbit Polyclonal Antibody

Numéro de catalogue: (PRSI5437)
Fournisseur: ProSci Inc.
Description: GAS Antibody: Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.
UOM: 1 * 1 EA
Image du produit-444-0921

Mélangeur orbital, résistant au CO2

Fournisseur: Thermo Fisher Scientific
Description: Cet agitateur orbital résistant au CO<sub>2</sub> assure un fonctionnement continu fiable, il est parfaitement adapté pour garder les cellules vivantes et florissantes au sein de l'environnement de travail. L'agitateur compact peut être utilisé à la fois dans et hors d'un incubateur CO<sub>2</sub>, offrant ainsi un maximum de flexibilité. Le boîtier de commande externe est équipé d'un affichage à LED, qui indique la vitesse et le temps, et de témoins lumineux de tr/min, temps, cycle et une alerte visuelle. Les applications incluent : culture de cellules mammifères, suspensions de bactéries, coloration et décoloration, procédures de lavage, hybridation, études de solubilité, procédures d'extraction et tests diagnostiques.

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Image non disponible-HAKA1560001B

Immersion Circulator, AC200

Numéro de catalogue: (HAKA1560001B)
Fournisseur: THERMO ELECTRON LED
Description: Thermo Scientific™ AC200 is ideal when applications require greater pumping performance, ramp programming, application alarms, and temperature ranges from 13 to 200 °C. Features include an enhanced digital display and easy-to-use touchpad settings, allowing you to easily tune the temperature to meet your specific application requirements.
UOM: 1 * 1 ST

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