Phénol 99,0-100,5, EMPROVE® ESSENTIAL USP, JP, Ph. Eur., ChP, extra_pure suitable for use as excipient, SAFC®
Fournisseur: MERCK PRODUCTION CHEMICALS
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Danger
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Synonyms:
Phenylalcohol, Carbolic acid, Hydroxybenzene
For full details of specification and hazards please see www.vwr.com or the VWR Chemicals catalogues
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Formule:
C₆H₅OH MW: 94.11 g/mol Point d'ébullition: 181.7 Point de fusion: 40.8 Densité: 1.0722 g/cm³ (20 °C) Point d'éclair: 81 Température de stockage: Température ambiante |
Numéro MDL:
MFCD00002143 Numéro CAS: 108-95-2 EINECS: 203-632-7 ONU: 1671 ADR: 6.1 II ATTEINDRE: 01-2119471329-32 Merck Index: 12,07390 |
Résultats des tests de spécification
Assay (bromatometric) | 99.0 - 100.5 % |
Assay (bromatometric, calc. on anhydrous substance) | 99.0 - 100.5 % |
Identity (IR-spectrum) | passes test |
Identity (wet chemistry) | passes test |
Appearance | colourless or faintly pink or faintly yellowish crystals or crystalline masses, deliquescent |
Appearance of solution (67 g/l, water) | clear and not more intensely coloured than reference solution B6 |
Acidic substances | passes test |
Solidification temperature | ≥ 39.5 °C |
Fe (Iron) | ≤ 1 ppm |
Benzene (HS-GC) | ≤ 2 ppm |
Methanol (HS-GC) | ≤ 3000 ppm |
Acetone (HS-GC) | ≤ 2 ppm |
Anisole | ≤ 10 ppm |
Cumene (HS-GC) | ≤ 70 ppm |
Methylisobutylketone (HS-GC) | ≤ 2 ppm |
Other residual solvents (ICH (Q3C)) | excluded by manufacturing process |
Residue on evaporation (105 °C, 1 h) | ≤ 0.05 % |
Residue on evaporation (105 °C) | ≤ 0.05 % |
Water (according to Karl Fischer) | ≤ 0.5 % |
Corresponds to Ph. Eur., ChP, JP, USP |
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