Imprimer

Human Recombinant EGF

Fournisseur: STEMCELL Technologies

78006 78006.1 78006.2
STMC78006EA 196 EUR
STMC78006 STMC78006.1 STMC78006.2
Human Recombinant EGF
Protéines et Peptides

Epidermal growth factor (EGF) is characterized by high affinity binding to various EGF receptors (EGFRs) and the production of mitogenic responses (Carpenter and Cohen). EGF promotes EGFR dimerization, resulting in activation of downstream pathways including PI3K, ERK1/2, JAK/STAT, β-catenin, and calcium signaling. EGF is secreted by the gut-associated salivary and Brunner’s glands, is found in a variety of body fluids, and stimulates cell proliferation and differentiation in rodent and neonatal human intestine (Wright et al.). Central nervous system stem cells also proliferate in response to the EGF stimulus (Reynolds and Weiss).


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