Imprimer

SC-236 ≥95% (par HPLC)

Fournisseur: ENZO LIFE SCIENCES

Synonyms: 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide, 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulphonamide

ALX270377M005 ALX270377M025
ENZOALX270377M005EA 141 EUR
ENZOALX270377M005 ENZOALX270377M025
SC-236 ≥95% (par HPLC)
SC-236

Highly selective and potent inhibitor of cyclooxygenase-2 (IC50=10nM for COX-2 versus IC50=17.8µM for COX-1) with antitumor properties. Exhibits longer half-life time and reduced gastric toxicity in fasting rat model. Has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. Potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.


  • COX inhibitor


White to off-white crystalline powder.


Soluble in DMSO.

Formule: C₁₆H₁₁ClF₃N₃O₂S
Température de stockage: Congélateur
Numéro MDL: MFCD00941297
Numéro CAS: 170569-86-5

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