Imprimer

DMOG 99 TLC_ASSAY_METHOD

Fournisseur: ENZO LIFE SCIENCES

Synonyms: N-[Methoxy(oxo)acetyl]glycine methyll ester, Dimethyloxaloylglycine, Methyl 2-((2-methoxy-2-oxoethyl)amino)-2-oxoacetate, DMOG

BMLEI3470010 BMLEI3470050
ENZOBMLEI3470010EA 89.1 EUR
ENZOBMLEI3470010 ENZOBMLEI3470050
DMOG 99 TLC_ASSAY_METHOD
DMOG

DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.


  • Prolyl-4-hydroxylase inhibitor


Off-white solid.


Soluble in DMSO (>25mg/ml), 100% ethanol (>25mg/ml) or dimethyl formamide; soluble also in PBS, pH7.2 (10mg/ml).

Formule: C₆H₉NO₅
MW: 175.14 g/mol
Température de stockage: Congélateur
Numéro MDL: MFCD05865098
Numéro CAS: 89464-63-1
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