Imprimer

Retinoic acid trans_all 95, Solid_yellow

Fournisseur: ENZO LIFE SCIENCES

Synonyms: all-trans-Retinoic acid, (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, ATRA, Vitamin A acid, Tretinoin

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Retinoic acid trans_all 95, Solid_yellow
Retinoic acid

Retinoic acid receptor ligand


Retinoic acid is the active metabolite of vitamin A. It is a potent modulator of growth and differentiation exerting its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. All trans retinoic acid binds to RAR α, β and γ subtypes with Kd values of 0.2, 0.4 and 0.2 nM respectively. RARs function as ligand-dependent transcription factors. Retinoic Acid also promotes the differentiation of mouse embryonic stem cells into adipocytes, neurons and glia in vitro. It guides development of the posterior part of the embryo.


Soluble in DMSO (25 mg/ml) or ethanol (10 mg/ml).

Formule: C₂₀H₂₈O₂
MW: 300.44 g/mol
Température de stockage: Congélateur
Numéro MDL: MFCD00001551
Numéro CAS: 302-79-4
EINECS: 206-129-0
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