Retinoic acid trans_all 95, Solid_yellow
Fournisseur: ENZO LIFE SCIENCES
Synonyms:
all-trans-Retinoic acid, (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, ATRA, Vitamin A acid, Tretinoin
Retinoic acid receptor ligand
Retinoic acid is the active metabolite of vitamin A. It is a potent modulator of growth and differentiation exerting its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. All trans retinoic acid binds to RAR α, β and γ subtypes with Kd values of 0.2, 0.4 and 0.2 nM respectively. RARs function as ligand-dependent transcription factors. Retinoic Acid also promotes the differentiation of mouse embryonic stem cells into adipocytes, neurons and glia in vitro. It guides development of the posterior part of the embryo.
Soluble in DMSO (25 mg/ml) or ethanol (10 mg/ml).
Formule:
C₂₀H₂₈O₂ MW: 300.44 g/mol Température de stockage: Congélateur |
Numéro MDL:
MFCD00001551 Numéro CAS: 302-79-4 EINECS: 206-129-0 |
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