Imprimer

Anti-ZAP70 Tyr315 + Tyr319 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Fournisseur: Bioss
BOSSBS-3478R-A680EA 881 EUR
BOSSBS-3478R-A680
Anti-ZAP70 Tyr315 + Tyr319 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anticorps
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterised by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Type: Primary
Antigen: ZAP70 Tyr315 + Tyr319
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse
Commander maintenant

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