Imprimer

Méthyle hydroxy-4 benzoate 99.0-102.0% (par acidimétrie), EMPROVE® ESSENTIAL NF, JP, Ph. Eur., BP, FCC suitable for use as excipient E218, SAFC®

Fournisseur: MERCK PRODUCTION CHEMICALS
Attention

Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester, Methyl Parahydroxybenzoate, Methyl 4-hydroxybenzoate

1.06757.5000 1.06757.9024
1.06757.5000EA 873 EUR
1.06757.5000 1.06757.9024
Méthyle hydroxy-4 benzoate 99.0-102.0% (par acidimétrie), EMPROVE® ESSENTIAL NF, JP, Ph. Eur., BP, FCC suitable for use as excipient E218, SAFC®
Méthyle hydroxy-4 benzoate
Formule: HOC₆H₄CO₂CH₃
MW: 152.15 g/mol
Point d'ébullition: 270…280 °C (1013 hPa)
Point de fusion: 125…128 °C
Densité: 1.1208 g/cm³ (137 °C)
Température de stockage: Température ambiante
Numéro MDL: MFCD00002352
Numéro CAS: 99-76-3
EINECS: 202-785-7
Merck Index: 13,06129
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Résultats des tests de spécification

Assay (Acidimetric) 99.0 - 102.0 %
Assay (HPLC) 99.0 - 100.5 %
Identity passes test
Appearance of solution passes test
Acidic substances passes test
Melting range (lower value) ≥ 125 °C
Melting range (upper value) ≤ 128 °C
Heavy metals (as Pb) ≤ 10 ppm
As (Arsenic) ≤ 3 ppm
Cd (Cadmium) ≤ 10 ppm
Cu (Copper) ≤ 10 ppm
Hg (Mercury) ≤ 1 ppm
Pb (Lead) ≤ 2 ppm
Zn (Zinc) ≤ 10 ppm
Related substances (HPLC) passes test
p-Hydroxy benzoic acid ≤ 0.5 %
Sum of all impurities ≤ 1.0 %
Largest unspecified impurity ≤ 0.5 %
Methanol (HS-GC) ≤ 3000 ppm
Other residual solvents (ICH Q3C) excluded by manufactoring process
Sulfated ash ≤ 0.05 %
Loss on drying (80 °C) ≤ 0.5 %
Corresponds to Ph Eur, BP, JP, NF, FCC


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