Imprimer

4,9-Diazadodécamethylenediamine ≥97%, solide incolore

Fournisseur: MP Biomedicals
Danger

Synonyms: N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine), Spermine

02152070.5 0215207001 0215207005
ICNA02152070.5EA 51.9 EUR
ICNA02152070.5 ICNA0215207001 ICNA0215207005
4,9-Diazadodécamethylenediamine ≥97%, solide incolore
4,9-Diazadodécamethylenediamine

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.


Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).


Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.


Attention: Research Use Only (RUO). Desiccate, store under nitrogen.

Formule: C₁₀H₂₆N₄
Point d'ébullition: 141…142 °C (0.5 mmHg)
Point de fusion: 28…30 °C (lit.)
Température de stockage: Réfrigérateur
Numéro MDL: MFCD00008215
Numéro CAS: 71-44-3

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Résultats des tests de spécification

Identity Test Passes
Purity ≥97%
FTIR Conforms to Standard
pH (0.5% aq soln) 11 - 14


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