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Numéro de catalogue: (PRSI3147)

Fournisseur: ProSci Inc.

Description: PHAP III Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

UOM: 1 * 1 EA

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Numéro de catalogue: (PRSI3152)

Fournisseur: ProSci Inc.

Description: PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

UOM: 1 * 1 EA

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Numéro de catalogue: (PRSI33-952)

Fournisseur: ProSci Inc.

Description: HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. [RefSeq].

UOM: 1 * 1 EA

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Numéro de catalogue: (PRSI96-750)

Fournisseur: ProSci Inc.

Description: Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. CD262 / DR5 Promotes the activation of NF-kappa-B. DR5 is essential for ER stress-induced apoptosis and is regulated by p53/TP53.

UOM: 1 * 1 EA

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Numéro de catalogue: (148-3183)

Fournisseur: Dr. Weigert

Description: neodisher® LaboClean UW is suitable for the automated cleaning of laboratory glassware and utensils in water analysis laboratories, in serological institutes and in the phosphates industry. Especially for laboratory glassware used for sensitive analyses, where residues of phosphorous compounds would adulterate analysis results.

UOM: 1 * 10 kg

MSMD Certificats Promotion

Numéro de catalogue: (IKAAU078310)

Fournisseur: IKA

Description: The magic LAB® is a unique and multi-functional small-scale laboratory machine. It is designed for mixing, dispersing, wet milling and incorporation of powders into liquids. The magic LAB® is most frequently used for the development of new products or for optimising of existing process techniques, particularly in the chemical, cosmetic, pharmaceutical and food industries. It is an ideal machine for continuous, circulating and batch processing with interchangeable modules. Many work parameters of the magic LAB® are identical to those of the IKA 2000 inline production machines: UTL, DR, CMS, MHD, MK and MKO. Therefore, the magic LAB® ensures a reliable scale-up by offering the possibility to work with the same method from formulation development to mass production. The basic in-line machine is equipped with the single-stage dispersing module ULTRA-TURRAX® UTL. It is best suited for batch applications and can be adapted for the manufacturing of dispersions from coarse to fine. Compared to a conventional stirrer, the mixing time is reduced by up to 50%. Depending on the application, the basic unit can be modified quickly with different working modules.

UOM: 1 * 1 ST

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Numéro de catalogue: (EHERL12258000CY)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Dibutylétain dichlorure 10 µg/ml en solution dans cyclohexane, Type de conditionnement: Glass bottle

UOM: 1 * 10 mL

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Fournisseur: Dr. Weigert

Description: Excellent material compatibility with first-class cleaning activity due to the singular formula based on alkalinity donors, surfactants and enzymes. When used for manual pre-cleaning the cleaner solution does not have to be rinsed off prior to automated reprocessing. No neutralising step necessary for automated reprocessing; therefore short program cycles.

Certificats

Numéro de catalogue: (EHERXA15950010AC)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Pentachloroanisole-[ring-13C6] 100 µg/ml in acetone, Type de conditionnement: Flacon Verre

UOM: 1 * 1,1 mL

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Numéro de catalogue: (EHERXA17714601AL)

Fournisseur: EHRENSTORFER

Description: Organic Standard, 2,4,6-Trichloroanisole-D5 100 µg/ml en solution dans acétonitrile, Type de conditionnement: Flacon Verre

UOM: 1 * 1 mL

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Fournisseur: EHRENSTORFER

Description: Organic Standard, 1,1,2-Trichloroéthane, Type de conditionnement: Flacon Verre

Numéro de catalogue: (EHERC17730000)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Acide 2,3,6-trichlorobenzoïque, Type de conditionnement: Flacon verre pour solides

UOM: 1 * 0,1 g

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Numéro de catalogue: (EHERXA16174810CY)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Dinonyl phthalate-[ring-D4] 100 µg/ml in cyclohexane, Type de conditionnement: Flacon Verre

UOM: 1 * 1 mL

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Numéro de catalogue: (EHERXA11859500CY)

Fournisseur: EHRENSTORFER

Description: Organic Standard, γ-Cyhalothrin 100 µg/ml in cyclohexane, Type de conditionnement: Flacon Verre

UOM: 1 * 1 mL

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Numéro de catalogue: (EHERL10934000CY)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Cadusafos 10 µg/ml in cyclohexane, Type de conditionnement: Flacon Verre

UOM: 1 * 10 mL

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Numéro de catalogue: (EHERL17810000CY)

Fournisseur: EHRENSTORFER

Description: Organic Standard, Tricyclazole 10 µg/ml in cyclohexane, Type de conditionnement: Flacon Verre

UOM: 1 * 10 mL

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