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Anti-CASP1 Rat Monoclonal Antibody

Fournisseur: ENZO LIFE SCIENCES
ALX804531C100
ENZOALX804531C100EA 510 EUR
ENZOALX804531C100
Anti-CASP1 Rat Monoclonal Antibody
Anticorps
Capases are a highly conserved family of cysteine proteases and are synthesized as inactive zymogens, which are cleaved at Asp-x sites during apoptosis, generating large and small subunits that heterodimerize to form the active enzyme. Caspase-1 is a member of the ICE/CED-3 family of caspases and is detected in the pro-form as a protein of 45 kDa.
Caspase-1 generates the bioactive form of the pro-inflammatory cytokine IL-1β from its biologically inactive precursor. Overexpression of caspase-1 in cells induces apoptosis, which can be inhibited by cytokine response modifier A (CrmA). Caspase-1More Product Information
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