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Anti-ZFHX3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Fournisseur: Bioss
BS-11805R-A488
BOSSBS-11805R-A488EA 893 EUR
BOSSBS-11805R-A488
Anti-ZFHX3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Anticorps
AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzymeMore Product Information
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